ZFIN ID: ZDB-GENE-990415-224
Gene Name: frizzled class receptor 2
Gene Symbol: fzd2
Sequence Ontology ID : SO:0000704

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Previous Names: fz-2 (1), fz2 (1), fz8, cb383 (1), wu:fb70g09, zg08

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(Including Attributions)
Location: Chr: 3 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have Wnt-activated receptor activity and Wnt-protein binding activity; involved in several processes, including animal organ development, cell migration, and cell surface receptor  ...
GENE EXPRESSION
All Expression Data: 17 figures from 7 publications
Directly Submitted Expression Data: 6 figures (18 images) from Thisse et al., 2001 [cb383]
Wild-type Stages, Structures: Gastrula:50%-epiboly (5.25h-5.66h) to Larval:Day 4 (96.0h-120.0h)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la028896Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sdu2 Small Deletion Exon 1 Unknown TALEN
    Targeting reagents:
    PHENOTYPE
    Data: 8 figures from 4 publications
    Observed in:
    DISEASE ASSOCIATED WITH fzd2 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    omodysplasia Omodysplasia 2 164745
    DISEASE ASSOCIATED WITH fzd2 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process determination of left/right symmetry (more)
    Cellular Component plasma membrane (more)
    Molecular Function transmembrane signaling receptor activity (more)
    GO Terms (all 21)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000539 (1)
  • InterPro:IPR015526 (1)
  • InterPro:IPR017981 (1)
  • InterPro:IPR020067 (1)
  • InterPro:IPR026550 (1)
  • InterPro:IPR036790 (1)
  • PROSITE:PS50038 (1)
  • PROSITE:PS50261 (1)
  • Pfam:PF01392 (1)
  • Pfam:PF01534 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA fzd2-201 (1) 2440
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM fzd2 No data available
    MARKER RELATIONSHIPS
    fzd2Contained in: [BAC] DKEY-194J22 (1) (order this)
    fzd2Encodes: [EST] cb383 (1) (order this), fb70g09 (1)
    [cDNA] MGC:65755 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131140 (1) 2360bp
    Genomic GenBank:CU062431 (1) 183293bp
    Select Tool
    Polypeptide UniProtKB:F1QBI2 (1) 550aa
    Sequence Clusters UniGene:12607 (1)
    Sequence Information (all 17)
    OTHER fzd2 GENE PAGES
  • Alliance (1)
  • Gene:30370 (1)
  • VEGA:OTTDARG00000027178 (1)
  • Ensembl(GRCz11):ENSDARG00000054438 (2)
  • ORTHOLOGY for fzd2 (Chr: 3)
    CITATIONS (45)