ZFIN ID: ZDB-GENE-990415-224
Gene Name: frizzled class receptor 2
Gene Symbol: fzd2
Previous Names: fz-2 (1), fz2 (1), fz8, cb383 (1), wu:fb70g09, zg08
Location: Chr: 3 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 17 figures from 7 publications
Directly Submitted Expression Data: 6 figures (18 images) from Thisse et al., 2001 [cb383]
Wild-type Stages, Structures: Gastrula:50%-epiboly (5.25h-5.66h) to Larval:Day 4 (96.0h-120.0h)
  adaxial cell, artery, axial chorda mesoderm, cardiovascular system (all 24) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la028896Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents: MO1-fzd2 (1), MO2-fzd2 (1), MO3-fzd2 (1)
    PHENOTYPE
    Data: 8 figures from 4 publications
    Observed in: cell migration, convergent extension involved in gastrulation, dorsal fin, endocrine pancreas development (all 17) expand
    DISEASE ASSOCIATED WITH fzd2 HUMAN ORTHOLOGNo data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process Wnt signaling pathway, calcium modulating pathway (more)
    Cellular Component plasma membrane (more)
    Molecular Function Wnt-activated receptor activity (more)
    GO Terms (all 21)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000539 (1)
  • InterPro:IPR015526 (1)
  • InterPro:IPR017981 (1)
  • InterPro:IPR020067 (1)
  • InterPro:IPR026550 (1)
  • PROSITE:PS50038 (1)
  • PROSITE:PS50261 (1)
  • Pfam:PF01392 (1)
  • Pfam:PF01534 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA fzd2-001 (1) 2440
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYSNo data available
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM fzd2 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    fzd2Contained in: [BAC] DKEY-194J22 (1) (order this)
    fzd2Encodes: [EST] cb383 (1) (order this), fb70g09 (1)
    [cDNA] MGC:65755 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131140 (1) 2360bp
    Genomic GenBank:CU062431 (1) 183293bp
    Select Tool
    Polypeptide UniProtKB:F1QBI2 (1) 550aa
    Sequence Clusters UniGene:12607 (1)
    Sequence Information (all 16)
    OTHER fzd2 GENE PAGES
  • Gene:30370 (1)
  • VEGA:OTTDARG00000027178 (1)
  • Ensembl(GRCz10):ENSDARG00000054438 (1)
  • ORTHOLOGY for fzd2 (Chr: 3)
    Species Symbol Chromosome Accession # Evidence
    Human FZD2 17
  • Gene:2535
  • OMIM:600667
  • HGNC:4040
  • Amino acid sequence comparison (2)
    Conserved genome location (synteny) (1)
    Mouse Fzd2 11
  • MGI:1888513
  • Gene:57265
  • Amino acid sequence comparison (1)
    Download Curated Orthology
    CITATIONS (37)