Gene
myca
- ID
- ZDB-GENE-990415-162
- Name
- MYC proto-oncogene, bHLH transcription factor a
- Symbol
- myca Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 24 Mapping Details/Browsers
- Description
- Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Acts upstream of or within hematopoietic stem cell differentiation; regulation of vasculature development; and vasculature development. Predicted to be located in nucleus. Is expressed in several structures, including digestive system; immature eye; nervous system; neural tube; and pronephros. Human ortholog(s) of this gene implicated in several diseases, including angiosarcoma; carcinoma (multiple); demyelinating disease; hematologic cancer (multiple); and prostate cancer (multiple). Orthologous to human MYC (MYC proto-oncogene, bHLH transcription factor).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 71 figures from 54 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:64149 (5 images)
Wild Type Expression Summary
- All Phenotype Data
- 1 Figure from Shi et al., 2014
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Burkitt lymphoma | Alliance | Burkitt lymphoma, somatic | 113970 |
Domain, Family, and Site Summary
No data available
Domain Details Per Protein
| Protein | Length |
|---|---|
|
UniProtKB:P52160
|
419 |
Interactions and Pathways
Plasmids
No data available