ZFIN ID: ZDB-GENE-990415-128
Gene Name: SIX homeobox 3b
Gene Symbol: six3b
Sequence Ontology ID : SO:0000704

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Previous Names: six3.2, six6 (1), cb347 (1)

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(Including Attributions)
Location: Chr: 12 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 60 figures from 40 publications
Directly Submitted Expression Data: 6 figures (18 images) from Thisse et al., 2001 [cb347]
Wild-type Stages, Structures: Gastrula:50%-epiboly (5.25h-5.66h) to Hatching:Long-pec (48.0h-60.0h)
  adenohypophysis, anterior axial hypoblast, axial hypoblast anterior region, axial mesoderm (all 41) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
ja53 Small Deletion Exon 1 Unknown TALEN
ja55 Small Deletion Exon 1 Unknown TALEN
sa24913 Point Mutation Unknown Premature Stop ENU
sa35303 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • vu87 Point Mutation Unknown Unknown ENU
    Targeting reagents: MO1-six3a,six3b, MO2-six3b (1), TALEN1-six3b (1)
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH six3b HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    holoprosencephaly 2 Holoprosencephaly 2 157170
    Schizencephaly 269160
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process embryonic camera-type eye morphogenesis (more)
    Cellular Component nucleus (more)
    Molecular Function DNA binding (more)
    GO Terms (all 10)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001356 (1)
  • InterPro:IPR009057 (1)
  • InterPro:IPR031701 (1)
  • InterPro:IPR032949 (1)
  • PROSITE:PS50071 (1)
  • Pfam:PF00046 (1)
  • Pfam:PF16878 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA six3b-001 (1) 1759
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM six3b
    Tg(UAS:six3b)
    MARKER RELATIONSHIPS
    six3bContained in: [BAC] DKEY-250C11 (1) (order this)
    six3bEncodes: [EST] cb347 (1) (order this), fa01b08
    [cDNA] MGC:73043 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131363 (1) 1722bp
    Genomic GenBank:CR932018 (1) 137736bp
    Select Tool
    Polypeptide UniProtKB:O73709 (1) 293aa
    Sequence Clusters UniGene:75402 (1)
    Sequence Information (all 17)
    OTHER six3b GENE PAGES
  • Alliance (1)
  • Gene:30636 (1)
  • VEGA:OTTDARG00000020580 (1)
  • Ensembl(GRCz10):ENSDARG00000054879 (1)
  • ORTHOLOGY for six3b (Chr: 12)
    CITATIONS (98)