ZFIN ID: ZDB-GENE-990415-101
Gene Name: homeobox B1a
Gene Symbol: hoxb1a    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: hoxb1, etID309950.3 (1), id:ibd3532, sb:eu402, Z-3

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 3 Mapping Details/Browsers
Description: Exhibits sequence-specific DNA binding activity. Involved in central nervous system development. Predicted to localize to the nucleus. Is expressed in several structures, including hindbrain; mesoderm; neural keel; neural plate; and neural rod. Orthologous to human HOXB1 (homeobox B1).
Genome Resources: Alliance (1),  Gene:30337 (1),  Ensembl(GRCz11):ENSDARG00000008174 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa1191 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa31326 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa33162 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • um189 Small Deletion Exon 1 Unknown TALEN
    um190 Indel Exon 1 Unknown TALEN
    um191 Indel Exon 1 Unknown TALEN
    um192 Indel Exon 1 Unknown TALEN
    um193 Small Deletion Exon 1 Unknown TALEN
    um194 Indel Exon 1 Unknown TALEN
    Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-hoxb1a N/A 12
    TALEN1-hoxb1a
    1
    TALEN2-hoxb1a 1
    TALEN3-hoxb1a
    1
    DISEASE ASSOCIATED WITH hoxb1a HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    Facial paresis, hereditary congenital, 3 614744
    DISEASE ASSOCIATED WITH hoxb1a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process rhombomere 4 development (more)
    Cellular Component nucleus (more)
    Molecular Function sequence-specific DNA binding (more)
    GO Terms (all 11)
    PROTEIN FAMILIES, DOMAINS AND SITES
    Type InterPro ID Name
    Conserved_site IPR017970 Homeobox, conserved site
    Domain IPR001356 Homeobox domain
    Domain IPR020479 Homeobox domain, metazoa
    Homologous_superfamily IPR009057 Homeobox-like domain superfamily
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA hoxb1a-201 (1)    Ensembl 1507
    ottdart00000001810 (1) 1860
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    CONSTRUCTS WITH SEQUENCES FROM hoxb1a
    Construct Regulatory Regions Coding Sequences Species Tg Lines Publications
    Tg(hoxb1a-Mmu.Hbb:EGFP) hoxb1a EGFP Danio rerioMus musculus 1 5
    Tg(hoxb1a-Mmu.Hbb:GAL4-VP16) hoxb1a GAL4VP16 Danio rerioMus musculus 1 3
    Tg(hoxb1a-SCP1:Ocu.Hbb2-Cre-2A-Cerulean) hoxb1aSCP 2ACeruleanCre Danio rerioOryctolagus cuniclus 1 1
    Tg(hsp70l:hoxb1a-MYC) hsp70l hoxb1aMYC Danio rerio 1 1
    TgBAC(hoxb1a:RFP) hoxb1a RFP Danio rerio 1 3
    MARKER RELATIONSHIPS
    hoxb1a Contained in: [BAC] DKEY-178D9 (1) (order this)
    [PAC] BUSM1-254O17 (2)
    hoxb1a Encodes: [EST] eu402 (1), ibd3532 (1)
    [cDNA] MGC:194377 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_131115 (1) 957 nt
    Genomic GenBank:AL645782 (1) 119385 nt
    Select Tool
    Polypeptide UniProtKB:B3DHZ4 (1) 316 aa
    Sequence Information (all 20)
    ORTHOLOGY for hoxb1a ( Chr: 3 )
    CITATIONS (142)