ZFIN ID: ZDB-GENE-990415-101
Gene Name: homeobox B1a
Gene Symbol: hoxb1a
Sequence Ontology ID : SO:0000704

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Previous Names: hoxb1, etID309950.3 (1), id:ibd3532, sb:eu402, Z-3

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(Including Attributions)
Location: Chr: 3 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Exhibits sequence-specific DNA binding activity; involved in hindbrain development and nervous system development; predicted to localize to the nucleus; orthologous to human HOXB1 (homeobox B1).
GENE EXPRESSION
All Expression Data: 95 figures from 62 publications
Directly Submitted Expression Data: 3 figures (4 images) from Kudoh et al., 2001 [ibd3532]
  6 figures (15 images) from Thisse et al., 2005 [eu402]
Wild-type Stages, Structures: Gastrula:75%-epiboly (8.0h-9.0h) to Hatching:Long-pec (48.0h-60.0h)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa1191 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa31326 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa33162 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • um189 Small Deletion Exon 1 Unknown TALEN
    um190 Indel Exon 1 Unknown TALEN
    um191 Indel Exon 1 Unknown TALEN
    um192 Indel Exon 1 Unknown TALEN
    um193 Small Deletion Exon 1 Unknown TALEN
    um194 Indel Exon 1 Unknown TALEN
    Targeting reagents:
    PHENOTYPE
    Data: 15 figures from 5 publications
    Observed in:
    DISEASE ASSOCIATED WITH hoxb1a HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    Facial paresis, hereditary congenital, 3 614744
    DISEASE ASSOCIATED WITH hoxb1a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process rhombomere 4 development (more)
    Cellular Component nucleus (more)
    Molecular Function sequence-specific DNA binding (more)
    GO Terms (all 11)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001356 (1)
  • InterPro:IPR009057 (1)
  • InterPro:IPR017970 (1)
  • InterPro:IPR020479 (1)
  • PROSITE:PS00027 (1)
  • PROSITE:PS50071 (1)
  • Pfam:PF00046 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA hoxb1a-001 (1) 1507
    ottdart00000001810 (1) 1860
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDS
    Addgene
    CONSTRUCTS WITH SEQUENCES FROM hoxb1a
    MARKER RELATIONSHIPS
    hoxb1aContained in: [BAC] DKEY-178D9 (1) (order this)
    [PAC] BUSM1-254O17 (2) (order this)
    hoxb1aEncodes: [EST] eu402 (1), ibd3532 (1) (order this)
    [cDNA] MGC:194377 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131115 (1) 957bp
    Genomic GenBank:AL645782 (1) 119385bp
    Select Tool
    Polypeptide UniProtKB:B3DHZ4 (1) 316aa
    Sequence Clusters UniGene:83326 (1)
    Sequence Information (all 21)
    OTHER hoxb1a GENE PAGES
  • Alliance (1)
  • Gene:30337 (1)
  • VEGA:OTTDARG00000001696 (1)
  • VEGA:OTTDARG00000019759 (1)
  • Ensembl(GRCz11):ENSDARG00000008174 (1)
  • ORTHOLOGY for hoxb1a (Chr: 3)
    CITATIONS (139)