ZFIN ID: ZDB-GENE-980526-521
Gene Name: hairy-related 4, tandem duplicate 1
Gene Symbol: her4.1    Nomenclature History

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Previous Names: her4, Hes5e (1), ch73-21g5.2 (1), wu:fe18g04 (1), wu:fq41c06 (1), zgc:55218

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 23 Mapping Details/Browsers
Description: Exhibits double-stranded DNA binding activity. Involved in Notch signaling pathway; nervous system development; and somite specification. Predicted to localize to nucleus. Is expressed in several structures, including anterior neural rod; ectoderm; nervous system; neural keel; and segmental plate.
Genome Resources: Alliance (1),  Gene:100149863 (1),  Ensembl(GRCz11):ENSDARG00000056732 (2)
GENE EXPRESSION
All Expression Data: 95 figures from 59 publications
Directly Submitted Expression Data: 4 figures (15 images) from Rauch et al., 2003 [fq41c06]
Wild-type Stages, Structures: Gastrula:Shield (6.0h-8.0h) to Adult (90d-730d, breeding adult)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Sequence Targeting Reagents
Targeting Reagent Created Alleles Publications
MO1-her4 N/A 4
MO2-her4 N/A 3
MO3-her4 N/A 1
PHENOTYPE No data available
DISEASE ASSOCIATED WITH her4.1 HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH her4.1 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process anterior/posterior pattern specification (more)
Cellular Component nucleus (more)
Molecular Function double-stranded DNA binding (more)
GO Terms (all 14)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA her4.1-201 (1)    Ensembl 963
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
SignaFish
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM her4.1
Construct Regulatory Regions Coding Sequences Species Tg Lines Publications
Tg(her4.1:h2az2a-mCherry) her4.1 h2az2amCherry Danio rerio 1 2
Tg(her4.1:jupa-EGFP) her4.1 EGFPjupa Danio rerio 1 2
tg(her4.1:mcherry) her4.1 mCherry Danio rerio 1 1
Tg(her4.1:mCherry,Cre-ERT2) her4.1 CreERT2mCherry Danio rerio 3 8
Tg(her4.1:NTR-KikGR) her4.1 KikGRNTR Danio rerio 1 3
Tg(her4.1:RTTA,myl7:EGFP) her4.1myl7 EGFPRTTA Danio rerio 1 2
Tg(her4.1:TETA-GBD-2A-mCherry) her4.1 mCherryTETA Danio rerio 2 7
tg2(her4.1:mcherry) her4.1 mCherry Danio rerio 1 1
MARKER RELATIONSHIPS
her4.1 Contained in: [BAC] CH73-21G5 (1)
her4.1 Encodes: [EST] bn0aa072zb08 (1), fq41c06 (1) (order this)
[cDNA] MGC:173865 (1), MGC:192073 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_001103128 (1)
Genomic GenBank:CU062502 (1) 62011 nt
Select Tool
Polypeptide UniProtKB:Q90466 (1) 152 aa
Sequence Information (all 12)
ORTHOLOGY for her4.1 ( Chr: 23 )
CITATIONS (135)