ZFIN ID: ZDB-GENE-980526-515
Gene Name: v-maf avian musculoaponeurotic fibrosarcoma oncogene homolog Ba
Gene Symbol: mafba    Nomenclature History

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Previous Names: mafb, MafB (1), kr, kreisler, krml (1), val, valentino, wu:fc22d11 (1), wu:fj82a09 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 23 Mapping Details/Browsers
Description: Predicted to have DNA-binding transcription factor activity and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Involved in several processes, including hindbrain development; lymphangiogenesis; and pronephric glomerulus development. Predicted to localize to nucleus. Is expressed in several structures, including hindbrain; hindbrain neural keel; neural plate; renal system; and vein. Human ortholog(s) of this gene implicated in Duane retraction syndrome and multicentric carpotarsal osteolysis syndrome. Orthologous to human MAFB (MAF bZIP transcription factor B).
Genome Resources: Alliance (1),  Gene:30210 (1),  Ensembl(GRCz11):ENSDARG00000017121 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
b337 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • nkgsaizgffm35aGt Transgenic Insertion Unknown Unknown DNA
    uq4bh Point Mutation Unknown Premature Stop ENU
    Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-mafba
    1
    CRISPR2-mafba
    1
    MO1-mafba N/A 2
    DISEASE ASSOCIATED WITH mafba HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    multicentric carpotarsal osteolysis syndrome Alliance Multicentric carpotarsal osteolysis syndrome 166300
    Duane retraction syndrome 3 617041
    DISEASE ASSOCIATED WITH mafba VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process abducens nucleus development (more)
    Cellular Component host cell nucleus (more)
    Molecular Function DNA binding (more)
    GO Terms (all 15)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS No data available
    INTERACTIONS AND PATHWAYS
    SignaFish
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM mafba No data available
    MARKER RELATIONSHIPS
    mafba Encodes: [EST] fc22d11 (1), fj82a09 (1), fa04g11 (1)
    [cDNA] MGC:136738 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_131015 (1) 3220 nt
    Genomic GenBank:CABZ01028915 (1) 11830 nt
    Polypeptide UniProtKB:A0A2U3TVD3 (1) 397 aa
    Sequence Information (all 21)
    ORTHOLOGY for mafba ( Chr: 23 )
    CITATIONS (141)