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ZIRC
ZFIN ID: ZDB-GENE-980526-41
Gene Name: sonic hedgehog signaling molecule b
Gene Symbol: shhb
Sequence Ontology ID : SO:0001217

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Previous Names: tiggy winkle hedgehog, twh, twhh

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(Including Attributions)
Location: Chr: 2 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have calcium ion binding activity and patched binding activity. Involved in several processes, including embryonic cranial skeleton morphogenesis; endocardial cell differentiation; and  ...
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la023573Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la028783Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa2069 Point Mutation Unknown Premature Stop ENU
    sa5719 Point Mutation Unknown Premature Stop ENU
    sa8431 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa25111 Point Mutation Unknown Premature Stop ENU
    Targeting reagents:
    PHENOTYPE
    Data: 2 figures from 2 publications
    Observed in:
    DISEASE ASSOCIATED WITH shhb HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    holoprosencephaly 3 Holoprosencephaly 3 142945
    solitary median maxillary central incisor Single median maxillary central incisor 147250
    Microphthalmia with coloboma 5 611638
    Schizencephaly 269160
    DISEASE ASSOCIATED WITH shhb VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process embryonic neurocranium morphogenesis (more)
    Cellular Component extracellular region (more)
    Molecular Function hydrolase activity (more)
    GO Terms (all 24)
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA shhb-201 (1) 2019
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS
    Addgene
    MARKER RELATIONSHIPS
    shhb Contained in: [BAC] DKEY-265A7 (1) (order this)
    shhb Encodes: [EST] eu390 (1)
    [cDNA] MGC:101003 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131199 (1) 1990 bp
    Genomic GenBank:BX510360 (1) 213323 bp Blast at MegaBLAST
    Polypeptide UniProtKB:A0A0B5JJZ7 (1) 416 aa
    Sequence Clusters UniGene:75752 (1)
    Sequence Information (all 21)
    ORTHOLOGY for shhb ( Chr: 2 )
    CITATIONS (151)