Gene
msx1a
- ID
- ZDB-GENE-980526-312
- Name
- muscle segment homeobox 1a
- Symbol
- msx1a Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 14 Mapping Details/Browsers
- Description
- Predicted to have DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Involved in otic placode formation. Predicted to localize to nucleus. Is expressed in several structures, including immature eye; nervous system; neural keel; pharyngeal arch; and regenerating fin. Human ortholog(s) of this gene implicated in cleft lip; cleft palate; orofacial cleft 5; tooth and nail syndrome; and tooth disease (multiple). Orthologous to human MSX1 (msh homeobox 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 31 figures from 21 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- cb435 (23 images)
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
Domain Details Per Protein
Protein | Length | Helix-turn-helix motif | Homeobox, conserved site |
---|---|---|---|
UniProtKB:Q90455
|
233 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available