ZFIN ID: ZDB-GENE-980526-135
Gene Name: Indian hedgehog homolog b
Gene Symbol: ihhb
Previous Names: ehh (1), hh[b] (1), hhb, echidna hedgehog, zgc:113262
Location: Chr: 6 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 25 figures from 25 publications
Wild-type Stages, Structures: Gastrula:Bud (10.0h-10.33h) to Larval:Day 6 (144.0h-168.0h)
  axis, ceratohyal bone, ceratohyal cartilage chondrocyte, diencephalon ventral region (all 18) expand
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS 
Allele Type Mutagen Suppliers
sa20623 Point Mutation ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents: MO1-ihhb (1), MO2-ihhb (1), MO3-ihhb (1)
    PHENOTYPE
    Data: 3 figures from Chung et al., 2013
    Observed in: glioblast (sensu Vertebrata) cell division, spinal cord glioblast (sensu Vertebrata), spinal cord neuron, spinal cord oligodendrocyte (all 6) expand
    DISEASE ASSOCIATED WITH ihhb HUMAN ORTHOLOG 
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    acrocapitofemoral dysplasia Acrocapitofemoral dysplasia 607778
    brachydactyly Brachydactyly, type A1 112500
    GENE ONTOLOGY 
    Ontology GO Term
    Biological Process striated muscle cell development (more)
    Cellular Component extracellular region (more)
    Molecular Function hydrolase activity (more)
    GO Terms (all 15)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000320 (1)
  • InterPro:IPR001657 (1)
  • InterPro:IPR001767 (1)
  • InterPro:IPR003586 (1)
  • InterPro:IPR003587 (1)
  • InterPro:IPR006141 (1)
  • InterPro:IPR009045 (1)
  • InterPro:IPR028992 (1)
  • PROSITE:PS50817 (1)
  • Pfam:PF01079 (1)
  • Pfam:PF01085 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA ihhb-001 (1) 1717
    ihhb-002 (1) 979
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM ihhb
    Tg(hsp70l:ihhb-mCherry)
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS 
    ihhbContained in: [BAC] CH211-237C6 (1) (order this)
    ihhbContains: [SNP] rs3727945 (1), rs3727946 (1)
    ihhbEncodes: [cDNA] MGC:113262 (1) (order this)
    SEQUENCE INFORMATION 
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131088 (1) 1479bp
    Genomic GenBank:CU655960 (1) 153771bp
    Select Tool
    Polypeptide UniProtKB:F1R9L0 (1) 412aa
    Sequence Clusters UniGene:75090 (1)
    Sequence Information (all 18)
    OTHER ihhb GENE PAGES 
  • Gene:30299 (1)
  • VEGA:OTTDARG00000034594 (1)
  • Ensembl(GRCz10):ENSDARG00000058815 (1)
  • ORTHOLOGY for ihhb (Chr: 6) 
    Species Symbol Chromosome Accession # Evidence
    Human IHH 2
  • Gene:3549
  • OMIM:600726
  • HGNC:5956
  • Amino acid sequence comparison (3)
    Conserved genome location (synteny) (1)
    Mouse Ihh 1
  • MGI:96533
  • Gene:16147
  • Amino acid sequence comparison (3)
    Conserved genome location (synteny) (1)
    Download Curated Orthology
    CITATIONS (71)