ZFIN ID: ZDB-GENE-980526-135
Gene Name: Indian hedgehog homolog b
Gene Symbol: ihhb
Previous Names: ehh (1), hh[b] (1), hhb, echidna hedgehog, zgc:113262
Location: Chr: 6   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 23 figures from 23 publications
Wild-type Stages, Structures: Gastrula:Bud (10.0h-10.33h) to Larval:Day 6 (144.0h-168.0h)
  ceratohyal bone, ceratohyal cartilage chondrocyte, diencephalon ventral region, floor plate (all 16) expand
Curated Microarray Expression: GEO (1)
MUTANTS AND TARGETED KNOCKDOWNS
Knockdown reagents: MO1-ihhb (1), MO2-ihhb (1), MO3-ihhb (1)

Allele Type Mutagen Suppliers
sa20623 Point Mutation ENU
PHENOTYPE
Data: 3 figures from Chung et al., 2013
Observed in: glioblast (sensu Vertebrata) cell division, spinal cord glioblast (sensu Vertebrata), spinal cord neuron, spinal cord oligodendrocyte (all 6) expand
DISEASE ASSOCIATED WITH ihhb HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
acrocapitofemoral dysplasia Acrocapitofemoral dysplasia 607778
brachydactyly Brachydactyly, type A1 112500
GENE ONTOLOGY
Ontology GO Term
Biological Process striated muscle cell development (more)
Cellular Component extracellular region (more)
Molecular Function hydrolase activity (more)
GO Terms (all 15)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000320 (1)
  • InterPro:IPR001657 (1)
  • InterPro:IPR001767 (1)
  • InterPro:IPR003586 (1)
  • InterPro:IPR003587 (1)
  • InterPro:IPR006141 (1)
  • InterPro:IPR009045 (1)
  • InterPro:IPR028992 (1)
  • PROSITE:PS50817 (1)
  • Pfam:PF01079 (1)
  • Pfam:PF01085 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA ihhb-001 (1) 1717
    ihhb-002 (1) 979
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM ihhb
    Tg(hsp70l:ihhb-mCherry)
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    ihhb Contained in: [BAC] CH211-237C6 (1) (order this)
    ihhb Contains: [SNP] rs3727945 (1), rs3727946 (1)
    ihhb Encodes: [cDNA] MGC:113262 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_131088 (1) 1479 bp
    Genomic GenBank:CU655960 (1) 153771 bp
    Select Tool
    Polypeptide UniProtKB:F1R9L0 (1) 412 aa
    Sequence Clusters UniGene:75090 (1)
    Sequence Information (all 18)
    OTHER ihhb GENE PAGES
  • Gene:30299 (1)
  • VEGA:OTTDARG00000034594 (1)
  • Ensembl(Zv9):ENSDARG00000058815 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA CL
    Zebrafish ihhb 6  
    Human IHH 2 (2q33-q35)
  • OMIM:600726
  • Gene:3549
  • Mouse Ihh 1 ( 38.55 cM)
  • MGI:96533
  • Gene:16147
  • Orthology Details
    CITATIONS (70)