ZFIN ID: ZDB-GENE-980526-118
Gene Name: neurotrophic tyrosine kinase, receptor, type 1
Gene Symbol: ntrk1
Sequence Ontology ID : SO:0000704

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Previous Names: trk, trkA (1)

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(Including Attributions)
Location: Chr: 16 Mapping Details/Browsers
GENE EXPRESSION
All Expression Data: 5 figures from 3 publications
Wild-type Stages, Structures: Segmentation:14-19 somites (16.0h-19.0h) to Larval:Days 7-13 (168.0h-14d, 4.5mm, 8 teeth)
  hindbrain anterior side, spinal cord, whole organism
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa14939 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa14955 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa32109 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • European Zebrafish Resource Center (EZRC) (order this)
  • sa36252 Point Mutation Unknown Splice Site ENU
    Targeting reagents: MO1-ntrk1 (1)
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH ntrk1 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    familial medullary thyroid carcinoma Medullary thyroid carcinoma, familial 155240
    hereditary sensory neuropathy Insensitivity to pain, congenital, with anhidrosis 256800
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process defense response to bacterium (more)
    Cellular Component integral component of membrane (more)
    Molecular Function ATP binding (more)
    GO Terms (all 17)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000719 (1)
  • InterPro:IPR001245 (1)
  • InterPro:IPR001611 (1)
  • InterPro:IPR002011 (1)
  • InterPro:IPR003599 (1)
  • InterPro:IPR007110 (1)
  • InterPro:IPR008266 (1)
  • InterPro:IPR011009 (1)
  • InterPro:IPR013783 (1)
  • InterPro:IPR017441 (1)
  • InterPro:IPR020461 (1)
  • InterPro:IPR020635 (1)
  • InterPro:IPR020777 (1)
  • InterPro:IPR031635 (1)
  • InterPro:IPR032675 (1)
  • PROSITE:PS00107 (1)
  • PROSITE:PS00109 (1)
  • PROSITE:PS00239 (1)
  • PROSITE:PS50011 (1)
  • PROSITE:PS50835 (1)
  • Pfam:PF07714 (1)
  • Pfam:PF13855 (1)
  • Pfam:PF16920 (1)
  • EC:2.7.10.1 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA ntrk1-001 (1) 2663
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM ntrk1
    Tg(mpeg1.1:ntrk1)
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    ntrk1Contained in: [BAC] DKEY-45N22 (1) (order this)
    ntrk1Encodes: [cDNA] MGC:193825 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001301356 (1) 3114bp
    Genomic GenBank:CR933818 (1) 243546bp Blast at MegaBLAST
    Polypeptide UniProtKB:F6P1M3 (1) 797aa
    Sequence Clusters UniGene:88619 (1)
    Sequence Information (all 16)
    OTHER ntrk1 GENE PAGES
  • Gene:30546 (1)
  • VEGA:OTTDARG00000027779 (1)
  • Ensembl(GRCz10):ENSDARG00000004586 (1)
  • ORTHOLOGY for ntrk1 (Chr: 16)
    CITATIONS (20)