Gene

nek10

ID
ZDB-GENE-130530-570
Name
NIMA-related kinase 10
Symbol
nek10 Nomenclature History
Previous Names
  • si:ch211-231m23.2
  • zmp:0000000567 (1)
Type
protein_coding_gene
Location
Chr: 16 Mapping Details/Browsers
Description
Predicted to have protein serine/threonine kinase activity. Predicted to be involved in positive regulation of MAP kinase activity and regulation of cell cycle G2/M phase transition. Is expressed in female organism. Human ortholog(s) of this gene implicated in primary ciliary dyskinesia 44. Orthologous to human NEK10 (NIMA related kinase 10).
Genome Resources
Note
None
Expression
All Expression Data
from Newman et al., 2019
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With nek10 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
primary ciliary dyskinesia 44 Alliance Ciliary dyskinesia, primary, 44 618781
Associated With nek10 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR008266 Tyrosine-protein kinase, active site
Binding_site IPR017441 Protein kinase, ATP binding site
Domain IPR000719 Protein kinase domain
Homologous_superfamily IPR011009 Protein kinase-like domain superfamily
Homologous_superfamily IPR016024 Armadillo-type fold
Repeat IPR000225 Armadillo
Domain Details Per Protein
Protein Length Armadillo Armadillo-type fold Protein kinase, ATP binding site Protein kinase domain Protein kinase-like domain superfamily Tyrosine-protein kinase, active site
UniProtKB:X1WEQ3 935
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Citations