ZFIN ID: ZDB-GENE-121031-4
Gene Name: chromodomain helicase DNA binding protein 3
Gene Symbol: chd3    Nomenclature History

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 7 Mapping Details/Browsers
Description: Predicted to have ATP binding activity and metal ion binding activity. Involved in central nervous system development and developmental growth. Predicted to localize to nucleus. Is expressed in blastomere and central nervous system. Orthologous to human CHD3 (chromodomain helicase DNA binding protein 3).
Genome Resources: Alliance (1),  Gene:568230 (1),  Ensembl(GRCz11):ENSDARG00000021405 (1)
GENE EXPRESSION
All Expression Data: 2 figures from Pfefferli et al., 2014
Wild-type Stages, Structures: Cleavage:2-cell (0.75h-1.0h) to Pharyngula:Prim-5 (24.0h-30.0h)
 
High Throughput Expression: Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa20909 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa34045 Point Mutation Unknown Unknown ENU
    sa40868 Point Mutation Unknown Unknown ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-chd3 N/A 1
    MO2-chd3 N/A 1
    DISEASE ASSOCIATED WITH chd3 HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    Snijders Blok-Campeau syndrome 618205
    DISEASE ASSOCIATED WITH chd3 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process central nervous system development (more)
    Cellular Component nucleus (more)
    Molecular Function ATP binding (more)
    GO Terms (all 10)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA chd3-201 (1)    Ensembl 8745
    Browsers: NCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM chd3 No data available
    MARKER RELATIONSHIPS
    chd3 Contained in: [BAC] DKEY-1C17 (order this), DKEY-19B23 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:XM_005172235 (1) 8053 nt
    Genomic GenBank:CR318653 (1) 235090 nt Blast at MegaBLAST
    Polypeptide UniProtKB:A0A2R8Q3B4 (1) 1820 aa
    Sequence Information (all 26)
    ORTHOLOGY for chd3 ( Chr: 7 )
    CITATIONS (23)