ZFIN ID: ZDB-GENE-101230-1
Gene Name: synaptopodin 2b
Gene Symbol: synpo2b    Nomenclature History

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Attributions

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Previous Names: im:7158034, si:ch211-108g16.2

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 1 Mapping Details/Browsers
Description: Predicted to have actin binding activity. Predicted to be involved in positive regulation of actin filament bundle assembly. Predicted to localize to Z disc; actin cytoskeleton; and nucleus. Is expressed in myotome. Orthologous to human SYNPO2 (synaptopodin 2).
Genome Resources: Alliance (1),  Gene:100006620 (1),  Ensembl(GRCz11):ENSDARG00000077157 (1)
GENE EXPRESSION
Directly Submitted Expression Data: 6 figures (11 images) from Thisse et al., 2004 [IMAGE:7158034]
Wild-type Stages, Structures: Segmentation:1-4 somites (10.33h-11.66h) to Hatching:Long-pec (48.0h-60.0h)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa1204 Point Mutation Unknown Missense, Splice Site ENU
sa9982 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa13742 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa16016 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa17339 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa45072 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • zko500a Small Deletion Unknown Unknown CRISPR
  • China Zebrafish Resource Center (CZRC) (order this)
  • zko500b Insertion Unknown Unknown CRISPR
  • China Zebrafish Resource Center (CZRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-synpo2b 1
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH synpo2b HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH synpo2b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process positive regulation of actin filament bundle assembly (more)
    Cellular Component actin cytoskeleton (more)
    Molecular Function actin binding (more)
    GO Terms (all 5)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA synpo2b-201 (1)    Ensembl 833
    synpo2b-202 (1)    Ensembl 3141
    Browsers: NCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM synpo2b No data available
    MARKER RELATIONSHIPS
    synpo2b Contained in: [BAC] CH211-108G16
    synpo2b Encodes: [EST] IMAGE:7158034 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:XM_017356099 (1)
    Genomic GenBank:BX927100 (1) 67582 nt
    Select Tool
    Polypeptide UniProtKB:A0A2R8QJD7 (1) 660 aa
    Sequence Information (all 10)
    ORTHOLOGY for synpo2b ( Chr: 1 )
    CITATIONS (16)