Gene

slc1a2a

ID
ZDB-GENE-100422-11
Name
solute carrier family 1 member 2a
Symbol
slc1a2a Nomenclature History
Previous Names
  • SLC1A2b (2)
  • EAAT2b
Type
protein_coding_gene
Location
Chr: 7 Mapping Details/Browsers
Description
Predicted to have symporter activity. Localizes to cone cell pedicle. Is expressed in brain; photoreceptor cell; and retinal neural layer. Human ortholog(s) of this gene implicated in early infantile epileptic encephalopathy 41. Orthologous to human SLC1A2 (solute carrier family 1 member 2).
Genome Resources
Note
None
Expression
All Expression Data
6 figures from 3 publications
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
Fig. 3 from Niklaus et al., 2017
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With slc1a2a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
early infantile epileptic encephalopathy 41 Alliance Developmental and epileptic encephalopathy 41 617105
Associated With slc1a2a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR018107 Sodium:dicarboxylate symporter, conserved site
Family IPR001991 Sodium:dicarboxylate symporter
Homologous_superfamily IPR036458 Sodium:dicarboxylate symporter superfamily
Domain Details Per Protein
Protein Length Sodium:dicarboxylate symporter Sodium:dicarboxylate symporter, conserved site Sodium:dicarboxylate symporter superfamily
UniProtKB:D7RVR8 548
UniProtKB:A0A1L1QZT2 38
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-slc1a2a polyclonal Guinea pig
  • IHC
1
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations