ZFIN ID: ZDB-GENE-090421-2
Gene Name: phosphodiesterase 6B, cGMP-specific, rod, beta
Gene Symbol: pde6b
Sequence Ontology ID : SO:0000704

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Location: Chr: 21 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have 3',5'-cyclic-GMP phosphodiesterase activity; predicted to be involved in G protein-coupled receptor signaling pathway, regulation of cytosolic calcium ion concentration, and retina  ...
GENE EXPRESSION
All Expression Data: 3 figures from 3 publications
Wild-type Stages, Structures: Larval:Day 4 (96.0h-120.0h) to Juvenile:Days 45-89 (45d-90d, 14 mm, 12 teeth)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa43623 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH pde6b HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    congenital stationary night blindness autosomal dominant 2 Night blindness, congenital stationary, autosomal dominant 2 163500
    retinitis pigmentosa 40 Retinitis pigmentosa-40 613801
    DISEASE ASSOCIATED WITH pde6b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process signal transduction (more)
    Molecular Function 3',5'-cyclic-nucleotide phosphodiesterase activity (more)
    GO Terms (all 5)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR002073 (1)
  • InterPro:IPR003018 (1)
  • InterPro:IPR003607 (1)
  • InterPro:IPR023088 (1)
  • InterPro:IPR023174 (1)
  • InterPro:IPR029016 (1)
  • InterPro:IPR036971 (1)
  • PROSITE:PS00126 (1)
  • PROSITE:PS51845 (1)
  • Pfam:PF00233 (1)
  • Pfam:PF01590 (1)
  • EC:3.1.4.- (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA pde6b-001 (1) 5593
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM pde6b No data available
    MARKER RELATIONSHIPS
    pde6bContained in: [BAC] DKEY-30K6 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_679910 (1) 5642bp
    Genomic GenBank:AL844141 (1) 257634bp Blast at MegaBLAST
    Polypeptide UniProtKB:E7F5I9 (1) 854aa
    Sequence Clusters UniGene:119812 (1)
    Sequence Information (all 18)
    OTHER pde6b GENE PAGES
  • Alliance (1)
  • Gene:559332 (1)
  • VEGA:OTTDARG00000031559 (1)
  • Ensembl(GRCz11):ENSDARG00000011671 (2)
  • ORTHOLOGY for pde6b (Chr: 21)
    CITATIONS (21)