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ZIRC
ZFIN ID: ZDB-GENE-090313-243
Gene Name: Rho guanine nucleotide exchange factor (GEF) 19
Gene Symbol: arhgef19    Nomenclature History

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Previous Name: si:dkey-21o19.4

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 23 Mapping Details/Browsers
Description: Predicted to have Rho guanyl-nucleotide exchange factor activity. Involved in epidermis development and neural tube closure. Is expressed in post-vent region. Orthologous to human ARHGEF19 (Rho guanine nucleotide exchange factor 19).
Genome Resources: Alliance (1),  Ensembl(GRCz11):ENSDARG00000078853 (2)
GENE EXPRESSION
All Expression Data: Fig. S2 from Miles et al., 2017
Wild-type Stages, Structures: Pharyngula:Prim-5 (24.0h-30.0h) to Pharyngula:Prim-5 (24.0h-30.0h)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa9613 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa9879 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa24325 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa29923 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa45800 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-arhgef19 N/A 1
    PHENOTYPE
    Data: Fig. 3 from Miles et al., 2017
    Observed in:
    DISEASE ASSOCIATED WITH arhgef19 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH arhgef19 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process epidermis development (more)
    Molecular Function Rho guanyl-nucleotide exchange factor activity (more)
    GO Terms (all 4)
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA arhgef19-202 (1)    Ensembl 1535
    Browsers: EnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM arhgef19 No data available
    MARKER RELATIONSHIPS
    arhgef19 Contained in: [BAC] DKEY-21O19 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    Genomic GenBank:CR925709 (1) 151006 bp
    Select Tool
    Polypeptide UniProtKB:E7EY47 (1) 958 aa
    Sequence Information (all 3)
    ORTHOLOGY for arhgef19 ( Chr: 23 )
    CITATIONS (11)