ZFIN is now using GRCz12tu for Genomic Data
Gene
rev1
- ID
- ZDB-GENE-081105-180
- Name
- REV1 DNA directed polymerase
- Symbol
- rev1 Nomenclature History
- Previous Names
-
- si:dkey-57a22.7
- Type
- protein_coding_gene
- Location
- Chr: 9 Mapping Details/Browsers
- Genome Assembly
- GRCz12tu
- Annotation Status
- Current
- Description
- Enables G-quadruplex DNA binding activity. Predicted to be involved in error-free translesion synthesis and error-prone translesion synthesis. Predicted to act upstream of or within DNA biosynthetic process and DNA repair. Predicted to be located in nucleus. Orthologous to human REV1 (REV1 DNA directed polymerase).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 1 figure from Chen et al., 2020
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Conserved_site | IPR025527 | HUWE1/REV1, ubiquitin-binding motif |
| Conserved_site | IPR047346 | DNA repair protein REV1, ubiquitin-binding motif 1/2 |
| Domain | IPR001126 | UmuC domain |
| Domain | IPR001357 | BRCT domain |
| Domain | IPR017961 | DNA polymerase, Y-family, little finger domain |
| Domain | IPR031991 | DNA repair protein Rev1, C-terminal |
| Domain | IPR053848 | DNA polymerase IV/DNA polymerase iota-like, thumb domain |
| Family | IPR012112 | DNA repair protein Rev1 |
| Homologous_superfamily | IPR036420 | BRCT domain superfamily |
| Homologous_superfamily | IPR036775 | DNA polymerase, Y-family, little finger domain superfamily |
| Homologous_superfamily | IPR038401 | Rev1, C-terminal domain superfamily |
| Homologous_superfamily | IPR043128 | Reverse transcriptase/Diguanylate cyclase domain |
| Homologous_superfamily | IPR043502 | DNA/RNA polymerase superfamily |
Domain Details Per Protein
| Protein | Additional Resources | Length | BRCT domain | BRCT domain superfamily | DNA polymerase IV/DNA polymerase iota-like, thumb domain | DNA polymerase, Y-family, little finger domain | DNA polymerase, Y-family, little finger domain superfamily | DNA repair protein Rev1 | DNA repair protein Rev1, C-terminal | DNA repair protein REV1, ubiquitin-binding motif 1/2 | DNA/RNA polymerase superfamily | HUWE1/REV1, ubiquitin-binding motif | Rev1, C-terminal domain superfamily | Reverse transcriptase/Diguanylate cyclase domain | UmuC domain |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| UniProtKB:A0A8M6Z8G9 | InterPro | 1201 | |||||||||||||
| UniProtKB:A0A8M3AVZ1 | InterPro | 1261 | |||||||||||||
| UniProtKB:A0A8M2BF27 | InterPro | 1262 | |||||||||||||
| UniProtKB:B0UY97 | InterPro | 1268 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available
- Genome Browsers