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General Information
ZIRC
ZFIN ID: ZDB-GENE-081104-306
Gene Name: cyclin-dependent kinase inhibitor 2A/B (p15, inhibits CDK4)
Gene Symbol: cdkn2a/b
Sequence Ontology ID : SO:0001217

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Previous Names: cdkn2b, ink4b (1), si:dkey-123o10.1

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(Including Attributions)
Location: Chr: 1 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Human ortholog(s) of this gene implicated in several diseases, including breast cancer (multiple); carcinoma (multiple); hematologic cancer (multiple); malignant glioma (multiple); and melanoma  ...
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa25583 Point Mutation Unknown Splice Site ENU
sa32685 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • zk1 Small Deletion Exon 1 Frameshift TALEN
    zk2 Small Deletion Exon 1 Frameshift TALEN
    Targeting reagents:
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH cdkn2a/b HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    melanoma and neural system tumor syndrome Melanoma and neural system tumor syndrome 155755
    Orolaryngeal cancer, multiple
    Pancreatic cancer/melanoma syndrome 606719
    {Melanoma, cutaneous malignant, 2} 155601
    DISEASE ASSOCIATED WITH cdkn2a/b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY No data available
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA cdkn2a/b-201 (1) 378
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    PLASMIDS
    Addgene
    CONSTRUCTS WITH SEQUENCES FROM cdkn2a/b No data available
    MARKER RELATIONSHIPS
    cdkn2a/b Contained in: [BAC] CH211-145B13 (1) (order this), DKEY-123O10 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_002660468 (1)
    Genomic GenBank:CT573245 (1) 196368 bp
    Select Tool
    Polypeptide UniProtKB:A0A2R8PZV6 (1) 129 aa
    Sequence Information (all 7)
    ORTHOLOGY for cdkn2a/b ( Chr: 1 )
    CITATIONS (24)