ZFIN ID: ZDB-GENE-081104-25
Gene Name: guanine nucleotide binding protein (G protein), q polypeptide
Gene Symbol: gnaq    Nomenclature History

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Names: gnaqa (1), Galpha q (1), si:ch73-270f14.2

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 5 Mapping Details/Browsers
Description: Predicted to have several functions, including G-protein beta/gamma-subunit complex binding activity; GTPase activator activity; and type 2A serotonin receptor binding activity. Predicted to be involved in action potential; adenylate cyclase-modulating G protein-coupled receptor signaling pathway; and phospholipase C-activating dopamine receptor signaling pathway. Predicted to localize to heterotrimeric G-protein complex. Is expressed in gill and nervous system. Human ortholog(s) of this gene implicated in Sturge-Weber syndrome and familial multiple nevi flammei. Orthologous to human GNAQ (G protein subunit alpha q).
Genome Resources: Alliance (1),  Gene:570108 (1),  Ensembl(GRCz11):ENSDARG00000011487 (1)
GENE EXPRESSION
All Expression Data: 3 figures from 3 publications
Wild-type Stages, Structures: Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth) to Adult (90d-730d, breeding adult)
 
PHENOTYPE No data available
DISEASE ASSOCIATED WITH gnaq HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
familial multiple nevi flammei Alliance Capillary malformations, congenital, 1, somatic, mosaic 163000
Sturge-Weber syndrome Alliance Sturge-Weber syndrome, somatic, mosaic 185300
DISEASE ASSOCIATED WITH gnaq VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process G protein-coupled receptor signaling pathway (more)
Cellular Component heterotrimeric G-protein complex (more)
Molecular Function G-protein beta/gamma-subunit complex binding (more)
GO Terms (all 13)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA gnaq-201 (1)    Ensembl 1745
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM gnaq
Construct Regulatory Regions Coding Sequences Species Tg Lines Publications
Tg(cryaa:Venus,mitfa:gnaq_Q209P) cryaamitfa gnaqVenus Danio rerio 3 1
MARKER RELATIONSHIPS
gnaq Contained in: [BAC] CH73-270F14 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_001144799 (1) 1745 nt
Genomic GenBank:CU468920 (1) 93429 nt
Select Tool
Polypeptide UniProtKB:B8JLJ7 (1) 359 aa
Sequence Information (all 5)
ORTHOLOGY for gnaq ( Chr: 5 )
CITATIONS (25)