ZFIN ID: ZDB-GENE-080213-3
Gene Name: DIS3 exosome endoribonuclease and 3'-5' exoribonuclease
Gene Symbol: dis3
Sequence Ontology ID : SO:0000704

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Previous Name: wu:fb08g12

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(Including Attributions)
Location: Chr: 1 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have 3'-5'-exoribonuclease activity and endonuclease activity; predicted to be involved in rRNA catabolic process and rRNA processing; predicted to localize to the cytoplasmic exosome  ...
GENE EXPRESSION
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la028126Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa24850 Point Mutation Unknown Premature Stop ENU
    sa25602 Point Mutation Unknown Premature Stop ENU
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH dis3 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH dis3 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process RNA catabolic process (more)
    Cellular Component exosome (RNase complex) (more)
    Molecular Function ribonuclease activity (more)
    GO Terms (all 7)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001900 (1)
  • InterPro:IPR002716 (1)
  • InterPro:IPR012340 (1)
  • InterPro:IPR022966 (1)
  • InterPro:IPR029060 (1)
  • InterPro:IPR033770 (1)
  • InterPro:IPR033771 (1)
  • PROSITE:PS01175 (1)
  • Pfam:PF00773 (1)
  • Pfam:PF13638 (1)
  • Pfam:PF17215 (1)
  • Pfam:PF17216 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    ncRNA dis3-002 (1) 757
    mRNA dis3-201 (1) 3247
     Withdrawn Transcriptsextinct
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM dis3 No data available
    MARKER RELATIONSHIPS
    dis3Contained in: [BAC] CH211-141I4 (order this), DKEY-15D12 (1) (order this)
    dis3Encodes: [EST] fb08g12
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_001336814 (1)
    Genomic GenBank:CR407598 (1) 153682bp
    Select Tool
    Polypeptide UniProtKB:E7FE01 (1) 950aa
    Sequence Clusters UniGene:51536 (1)
    Sequence Information (all 25)
    OTHER dis3 GENE PAGES
  • Alliance (1)
  • Gene:100003553 (1)
  • VEGA:OTTDARG00000033634 (1)
  • ORTHOLOGY for dis3 (Chr: 1)
    CITATIONS (16)