Gene

kif22

ID
ZDB-GENE-080204-34
Name
kinesin family member 22
Symbol
kif22 Nomenclature History
Previous Names
  • zKIF22 (1)
  • zgc:171724
Type
protein_coding_gene
Location
Chr: 12 Mapping Details/Browsers
Description
Predicted to have ATPase activity; microtubule binding activity; and microtubule motor activity. Involved in several processes, including central nervous system development; somitogenesis; and thigmotaxis. Predicted to localize to kinesin complex and microtubule. Is expressed in brain. Human ortholog(s) of this gene implicated in spondyloepimetaphyseal dysplasia with joint laxity type 2. Orthologous to human KIF22 (kinesin family member 22).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
2 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
4 figures from Blaker-Lee et al., 2012
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With kif22 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
spondyloepimetaphyseal dysplasia with joint laxity type 2 Alliance Spondyloepimetaphyseal dysplasia with joint laxity, type 2 603546
Associated With kif22 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR019821 Kinesin motor domain, conserved site
Domain IPR001752 Kinesin motor domain
Family IPR026986 Kinesin-like protein KIF22 (Kid)
Family IPR027640 Kinesin-like protein
Homologous_superfamily IPR010994 RuvA domain 2-like
Homologous_superfamily IPR027417 P-loop containing nucleoside triphosphate hydrolase
Homologous_superfamily IPR036961 Kinesin motor domain superfamily
Domain Details Per Protein
Protein Length Kinesin-like protein Kinesin-like protein KIF22 (Kid) Kinesin motor domain Kinesin motor domain, conserved site Kinesin motor domain superfamily P-loop containing nucleoside triphosphate hydrolase RuvA domain 2-like
UniProtKB:B7ZV80 634
UniProtKB:A8WFU8 634
UniProtKB:A0A0R4IAJ7 148
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations