Gene

kif22

ID

ZDB-GENE-080204-34

Name

kinesin family member 22

Symbol

kif22 Nomenclature History

Previous Names

zKIF22 (1)
zgc:171724

Type

protein_coding_gene

Location

Chr: 12 Mapping Details/Browsers

Description

Predicted to have ATPase activity; microtubule binding activity; and microtubule motor activity. Involved in several processes, including central nervous system development; somitogenesis; and thigmotaxis. Predicted to localize to kinesin complex and microtubule. Is expressed in brain. Orthologous to human KIF22 (kinesin family member 22).

Genome Resources

Note

None

Expression

All Expression Data

2 figures from 2 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

Thisse Expression Data

Wild Type Expression Summary

Phenotype

All Phenotype Data: 4 figures from Blaker-Lee et al., 2012
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With kif22 Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
spondyloepimetaphyseal dysplasia with joint laxity type 2	Alliance	Spondyloepimetaphyseal dysplasia with joint laxity, type 2	603546

Associated With kif22 Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Conserved_site	IPR019821	Kinesin motor domain, conserved site
Domain	IPR001752	Kinesin motor domain
Family	IPR026986	Kinesin-like protein KIF22 (Kid)
Family	IPR027640	Kinesin-like protein
Homologous_superfamily	IPR010994	RuvA domain 2-like
Homologous_superfamily	IPR027417	P-loop containing nucleoside triphosphate hydrolase
Homologous_superfamily	IPR036961	Kinesin motor domain superfamily

Domain Details Per Protein

Protein	Length	Kinesin-like protein	Kinesin-like protein KIF22 (Kid)	Kinesin motor domain	Kinesin motor domain, conserved site	Kinesin motor domain superfamily	P-loop containing nucleoside triphosphate hydrolase	RuvA domain 2-like
UniProtKB:B7ZV80 InterPro	634
UniProtKB:A8WFU8 InterPro	634
UniProtKB:A0A0R4IAJ7 InterPro	148

Transcripts

Genome Browsers

Type	Name	Length (nt)	Analysis
mRNA	kif22-201 (1) Ensembl	745 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
mRNA	kif22-202 (1) Ensembl	2287 nt	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

Interactions and Pathways

No data available

Antibodies

No data available

Plasmids

No data available

Constructs

Marker Relationships

Sequences

Orthology

Gene Tree: Ensembl

Citations