| ZFIN ID: ZDB-GENE-080204-34 |
| Gene Name: | kinesin family member 22 | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Gene Symbol: | kif22 Nomenclature History |
{{control.fieldName}} Edit
Attributions
|
||||||||||||
| Previous Names: | zKIF22 (1), zgc:171724 | |||||||||||||
Add new Alias
Attributions for Alias: {{control.newAlias}}
Delete Alias:(Including Attributions) |
||||||||||||||
| Gene Type: | protein_coding_gene | |||||||||||||
| Location: | Chr: 12 Mapping Details/Browsers | |||||||||||||
| Description: | Predicted to have ATPase activity; microtubule binding activity; and microtubule motor activity. Involved in several processes, including central nervous system development; somitogenesis; and thigmotaxis. Predicted to localize to kinesin complex and microtubule. Is expressed in brain. Orthologous to human KIF22 (kinesin family member 22). | |||||||||||||
| Genome Resources: | Alliance (1), Gene:561788 (1), Ensembl(GRCz11):ENSDARG00000102624 (1) | |||||||||||||
| All Expression Data: | 2 figures from 2 publications |
| Wild-type Stages, Structures: | Blastula:256-cell (2.5h-2.75h) to Hatching:Long-pec (48.0h-60.0h) |
| High Throughput Expression: | Expression Atlas (1) |
MUTATIONS AND SEQUENCE TARGETING REAGENTS
| Allele | Type | Localization | Consequence | Mutagen | Suppliers |
|---|---|---|---|---|---|
| sa22020 | Point Mutation | Unknown | Premature Stop | ENU |
|
| sa35201 | Point Mutation | Unknown | Premature Stop | ENU |
|
PHENOTYPE
| Data: | 4 figures from Blaker-Lee et al., 2012 |
| Observed in: |
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| Spondyloepimetaphyseal dysplasia with joint laxity, type 2 | 603546 |
GENE ONTOLOGY
| Ontology | GO Term |
|---|---|
| Biological Process | axonogenesis (more) |
| Cellular Component | cytoplasm (more) |
| Molecular Function | protein binding (more) |
| Type | Name | Length (nt) | Analysis | |
|---|---|---|---|---|
| mRNA |
kif22-201
(1)
|
745 |
Select Tool
|
|
|
kif22-202
(1)
|
2287 |
Select Tool
|
| Browsers: UCSC, NCBI, Ensembl, ZFIN |
INTERACTIONS AND PATHWAYS
ANTIBODIES
No data available
PLASMIDS
No data available
CONSTRUCTS WITH SEQUENCES FROM kif22
No data available
MARKER RELATIONSHIPS
| kif22 Contained in: | [BAC] CH211-149K17 |
| kif22 Encodes: | [cDNA] MGC:171724 (1), MGC:198215 (1), MGC:198219 (1) |
SEQUENCE INFORMATION
| Type | Accession # | Length (nt/aa) | Analysis |
|---|---|---|---|
| RNA | RefSeq:NM_001113591 (1) |
Select Tool
|
|
| Genomic | GenBank:AL929469 (1) | 146415 nt | |
| Polypeptide | UniProtKB:A8WFU8 (1) | 634 aa |
Select Tool
|
ORTHOLOGY for kif22 (
Chr:
12
)
CITATIONS (23)