ZFIN ID: ZDB-GENE-080204-34
Gene Name: kinesin family member 22
Gene Symbol: kif22    Nomenclature History

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Previous Names: zKIF22 (1), zgc:171724

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 12 Mapping Details/Browsers
Description: Predicted to have ATPase activity; microtubule binding activity; and microtubule motor activity. Involved in several processes, including central nervous system development; somitogenesis; and thigmotaxis. Predicted to localize to kinesin complex and microtubule. Is expressed in brain. Orthologous to human KIF22 (kinesin family member 22).
Genome Resources: Alliance (1),  Gene:561788 (1),  Ensembl(GRCz11):ENSDARG00000102624 (1)
GENE EXPRESSION
All Expression Data: 2 figures from 2 publications
Wild-type Stages, Structures: Blastula:256-cell (2.5h-2.75h) to Hatching:Long-pec (48.0h-60.0h)
 
High Throughput Expression: Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa22020 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa35201 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-kif22 N/A 2
    DISEASE ASSOCIATED WITH kif22 HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    Spondyloepimetaphyseal dysplasia with joint laxity, type 2 603546
    DISEASE ASSOCIATED WITH kif22 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process axonogenesis (more)
    Cellular Component cytoplasm (more)
    Molecular Function protein binding (more)
    GO Terms (all 19)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA kif22-201 (1)    Ensembl 745
    kif22-202 (1)    Ensembl 2287
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM kif22 No data available
    MARKER RELATIONSHIPS
    kif22 Contained in: [BAC] CH211-149K17
    kif22 Encodes: [cDNA] MGC:171724 (1), MGC:198215 (1), MGC:198219 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001113591 (1)
    Genomic GenBank:AL929469 (1) 146415 nt
    Select Tool
    Polypeptide UniProtKB:A8WFU8 (1) 634 aa
    Sequence Information (all 20)
    ORTHOLOGY for kif22 ( Chr: 12 )
    CITATIONS (23)