ZFIN ID: ZDB-GENE-080204-14
Gene Name: dickkopf WNT signaling pathway inhibitor 2
Gene Symbol: dkk2
Sequence Ontology ID : SO:0000704

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Previous Name: zgc:171574

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(Including Attributions)
Location: Chr: 1 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have co-receptor binding activity and receptor antagonist activity; involved in liver development and neuromast development; predicted to localize to the extracellular space; orthologous  ...
GENE EXPRESSION
All Expression Data: 9 figures from 7 publications
Wild-type Stages, Structures: Pharyngula:Prim-5 (24.0h-30.0h) to Larval:Protruding-mouth (72.0h-96.0h, 3.5mm)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la028178Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • zko974a Small Deletion Unknown Unknown CRISPR
    Targeting reagents:
    PHENOTYPE
    Data: Fig. 2 from Wada et al., 2013
    Observed in:
    DISEASE ASSOCIATED WITH dkk2 HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH dkk2 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process liver development (more)
    Cellular Component extracellular region (more)
    Molecular Function molecular_function (more)
    GO Terms (all 6)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR006796 (1)
  • InterPro:IPR039863 (1)
  • Pfam:PF04706 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA dkk2-001 (1) 1357
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM dkk2
    MARKER RELATIONSHIPS
    dkk2Contained in: [BAC] DKEY-84C11 (1) (order this)
    dkk2Encodes: [cDNA] MGC:171574 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001111209 (1) 1373bp
    Genomic GenBank:CR855327 (1) 183806bp
    Select Tool
    Polypeptide UniProtKB:A8KB56 (1) 243aa
    Sequence Clusters UniGene:82155 (1)
    Sequence Information (all 13)
    OTHER dkk2 GENE PAGES
  • Alliance (1)
  • Gene:792404 (1)
  • VEGA:OTTDARG00000029997 (1)
  • Ensembl(GRCz11):ENSDARG00000076420 (2)
  • ORTHOLOGY for dkk2 (Chr: 1)
    CITATIONS (33)