ZFIN ID: ZDB-GENE-080130-3
Gene Name: solute carrier family 12 (sodium/potassium/chloride transporter), member 1
Gene Symbol: slc12a1
Previous Names: nkcc2 (1), si:ch73-34a12.1
Location: Chr: 18 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 25 figures from 12 publications
Wild-type Stages, Structures: Segmentation:26+ somites (22.0h-24.0h) to Adult (90d-730d, breeding adult)
  developing mesonephric nephron, distal early tubule, mesonephric duct apical plasma membrane, pronephric distal early tubule (all 5) expand
MUTATIONS AND SEQUENCE TARGETING REAGENTSNo data available
PHENOTYPE No data available
DISEASE ASSOCIATED WITH slc12a1 HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
Bartter disease type 1 Bartter syndrome, type 1 601678
GENE ONTOLOGY
Ontology GO Term
Biological Process ion transport (more)
Cellular Component apical plasma membrane (more)
Molecular Function cation:chloride symporter activity (more)
GO Terms (all 8)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR002443 (1)
  • InterPro:IPR002445 (1)
  • InterPro:IPR004841 (1)
  • InterPro:IPR004842 (1)
  • InterPro:IPR018491 (1)
  • Pfam:PF00324 (1)
  • Pfam:PF03522 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA ottdart00000062234 (1) 1983
     Withdrawn Transcriptsextinct
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYSNo data available
    ANTIBODIES
    Ab1-slc12a (1)
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM slc12a1 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    slc12a1Contained in: [BAC] CH73-34A12 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_009293403 (1) 4799bp
    Genomic GenBank:CU498833 (1) 66872bp
    Select Tool
    Polypeptide UniProtKB:A0A0R4IMU6 (1) 681aa
    Sequence Clusters UniGene:156611 (1)
    Sequence Information (all 8)
    OTHER slc12a1 GENE PAGES
  • Gene:100329975 (1)
  • VEGA:OTTDARG00000043018 (1)
  • ORTHOLOGY for slc12a1 (Chr: 18)
    Species Symbol Chromosome Accession # Evidence
    Human SLC12A1 15
  • Gene:6557
  • OMIM:600839
  • HGNC:10910
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Mouse Slc12a1 2
  • MGI:103150
  • Gene:20495
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Download Curated Orthology
    CITATIONS (24)