ZFIN ID: ZDB-GENE-080130-3
Gene Name: solute carrier family 12 (sodium/potassium/chloride transporter), member 1
Gene Symbol: slc12a1
Previous Names: nkcc2 (1), si:ch73-34a12.1
Location: Chr: 18 Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 24 figures from 11 publications
Wild-type Stages, Structures: Segmentation:26+ somites (22.0h-24.0h) to Adult (90d-730d, breeding adult)
  distal early tubule, mesonephric duct apical plasma membrane, pronephric distal early tubule, pronephric distal late tubule
MUTATIONS AND SEQUENCE TARGETING REAGENTSNo data available
PHENOTYPE No data available
DISEASE ASSOCIATED WITH slc12a1 HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
Bartter disease Bartter syndrome, type 1 601678
GENE ONTOLOGY
Ontology GO Term
Biological Process ion transport (more)
Cellular Component apical plasma membrane (more)
Molecular Function cation:chloride symporter activity (more)
GO Terms (all 8)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR002443 (1)
  • InterPro:IPR002445 (1)
  • InterPro:IPR004841 (1)
  • InterPro:IPR004842 (1)
  • InterPro:IPR013612 (1)
  • InterPro:IPR018491 (1)
  • Pfam:PF00324 (1)
  • Pfam:PF03522 (1)
  • Pfam:PF08403 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA si:ch73-34a12.1-001 (1) 1983
     Withdrawn Transcriptsextinct
    GENE PRODUCT DESCRIPTION
    ANTIBODIES
    Ab1-slc12a (1)
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM slc12a1 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    slc12a1Contained in: [BAC] CH73-34A12 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:XM_009293403 (1) 2501bp
    Genomic GenBank:CU498833 (1) 66872bp
    Select Tool
    Polypeptide UniProtKB:F1R476 (1) 815aa
    Sequence Clusters UniGene:156611 (1)
    Sequence Information (all 10)
    OTHER slc12a1 GENE PAGES
  • Gene:100329975 (1)
  • VEGA:OTTDARG00000043018 (1)
  • ORTHOLOGY for slc12a1 (Chr: 18)
    Species Symbol Chromosome Accession # Evidence
    Human SLC12A1 15
  • Gene:6557
  • OMIM:600839
  • HGNC:10910
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Mouse Slc12a1 2
  • MGI:103150
  • Gene:20495
  • Amino acid sequence comparison (1)
    Conserved genome location (synteny) (1)
    Download Curated Orthology
    CITATIONS (22)