header logo image header logo text
Downloads Login
Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-071218-6
Gene Name: leucine-rich repeat kinase 2
Gene Symbol: lrrk2
Sequence Ontology ID : SO:0000704

{{control.fieldName}} Edit

ID: {{control.nomenID}}
{{control.fieldName}}:
Reason:
Comments:

Attributions

{{pub.zdbID}}
Previous Name:

Add new Alias

Alias
Attribution

Attributions for Alias: {{control.newAlias}}

{{pub.zdbID}}

Delete Alias:

(Including Attributions)
Location: Chr: 25 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Predicted to have volume-sensitive anion channel activity; predicted to be involved in anion transmembrane transport; predicted to localize to the cytoplasm and ion channel complex; orthologous to  ...
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa5114 Point Mutation Unknown Splice Site ENU
sa6813 Point Mutation Unknown Premature Stop ENU
sa6814 Point Mutation Unknown Splice Site ENU
sa8399 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa38142 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • zf2079 Small Deletion Exon 44 Frameshift, Premature Stop ZINC_FINGER_NUCLEASE
    Targeting reagents:
    DISEASE ASSOCIATED WITH lrrk2 HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    autosomal dominant Parkinson's disease 8 {Parkinson disease 8} 607060
    DISEASE ASSOCIATED WITH lrrk2 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process phosphorylation (more)
    Cellular Component cytoplasm (more)
    Molecular Function ATP binding (more)
    GO Terms (all 26)
    TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA lrrk2-201 (1) 9170
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM lrrk2 No data available
    MARKER RELATIONSHIPS
    lrrk2Contained in: [BAC] CH73-316L9 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001201456 (1) 9171bp
    Genomic GenBank:CU855815 (1) 108410bp
    Select Tool
    Polypeptide UniProtKB:D9IG64 (1) 2533aa
    Sequence Clusters UniGene:120864 (1)
    Sequence Information (all 15)
    ORTHOLOGY for lrrk2 (Chr: 25)
    CITATIONS (21)