ZFIN ID: ZDB-GENE-070912-458
Gene Name: ATR serine/threonine kinase
Gene Symbol: atr
Sequence Ontology ID : SO:0000704

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Previous Name: si:dkey-231j24.1

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(Including Attributions)
Location: Chr: 2 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 2 figures from 2 publications
Wild-type Stages, Structures: Segmentation:1-4 somites (10.33h-11.66h) to Pharyngula:Prim-5 (24.0h-30.0h)
 
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la023474Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa6829 Point Mutation Unknown Premature Stop ENU
    sa14005 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa14645 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa15319 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa19711 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa32869 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa32870 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa38321 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa39800 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Targeting reagents:
    PHENOTYPE
    Data: 4 figures from Stiff et al., 2016
    Observed in:
    DISEASE ASSOCIATED WITH atr HUMAN ORTHOLOG
    Disease Ontology Term OMIM Term OMIM Phenotype ID
    Seckel syndrome 1 Seckel syndrome 1 210600
    ?Cutaneous telangiectasia and cancer syndrome, familial 614564
    DISEASE ASSOCIATED WITH atr VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process intrinsic apoptotic signaling pathway in response to DNA damage (more)
    Cellular Component nucleus (more)
    Molecular Function ATP binding (more)
    GO Terms (all 13)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000403 (1)
  • InterPro:IPR003151 (1)
  • InterPro:IPR003152 (1)
  • InterPro:IPR011009 (1)
  • InterPro:IPR011990 (1)
  • InterPro:IPR012993 (1)
  • InterPro:IPR014009 (1)
  • InterPro:IPR016024 (1)
  • InterPro:IPR018936 (1)
  • InterPro:IPR036940 (1)
  • PROSITE:PS00916 (1)
  • PROSITE:PS50290 (1)
  • PROSITE:PS51189 (1)
  • PROSITE:PS51190 (1)
  • Pfam:PF00454 (1)
  • Pfam:PF02259 (1)
  • Pfam:PF02260 (1)
  • Pfam:PF08064 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA atr-001 (1) 8277
    ncRNA atr-002 (1) 770
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM atr No data available
    MARKER RELATIONSHIPS
    atrContained in: [BAC] DKEY-231J24 (1) (order this), DKEYP-13A3 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    Genomic GenBank:CR377211 (1) 186342bp
    Select Tool
    Polypeptide UniProtKB:F1QMM7 (1) 2635aa
    Sequence Information (all 3)
    OTHER atr GENE PAGES
  • Alliance (1)
  • VEGA:OTTDARG00000024280 (1)
  • Ensembl(GRCz11):ENSDARG00000079625 (2)
  • ORTHOLOGY for atr (Chr: 2)
    CITATIONS (26)