ZFIN ID: ZDB-GENE-070808-1
Gene Name: ADAM metallopeptidase domain 8b
Gene Symbol: adam8b    Nomenclature History

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Previous Name: CD156b

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 12 Mapping Details/Browsers
Description: Predicted to have metalloendopeptidase activity. Predicted to be involved in proteolysis. Predicted to localize to integral component of membrane. Is expressed in ovarian follicle stage I; ovarian follicle stage II; ovarian follicle stage III; and ovarian follicle stage IV. Orthologous to human ADAM8 (ADAM metallopeptidase domain 8).
Genome Resources: Alliance (1),  Gene:100005593 (1),  Ensembl(GRCz11):ENSDARG00000057644 (2)
GENE EXPRESSION
All Expression Data: 3 figures from 2 publications
Wild-type Stages, Structures: Adult (90d-730d, breeding adult) to Adult (90d-730d, breeding adult)
 
High Throughput Expression: Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa6236 Point Mutation Unknown Premature Stop ENU
sa10008 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa22036 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa41968 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • PHENOTYPE No data available
    DISEASE ASSOCIATED WITH adam8b HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH adam8b VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process proteolysis (more)
    Cellular Component integral component of membrane (more)
    Molecular Function metalloendopeptidase activity (more)
    GO Terms (all 5)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA adam8b-201 (1)    Ensembl 3402
    adam8b-202 (1)    Ensembl 741
    Browsers: NCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM adam8b No data available
    MARKER RELATIONSHIPS
    adam8b Contained in: [BAC] DKEY-14G24 (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:XM_003199573 (1) 2721 nt
    Genomic GenBank:CR854953 (1) 85566 nt
    Select Tool
    Polypeptide UniProtKB:E7F6J8 (1) 819 aa
    Sequence Information (all 9)
    ORTHOLOGY for adam8b ( Chr: 12 )
    CITATIONS (21)