ZFIN ID: ZDB-GENE-070511-1
Gene Name: protein kinase C, zeta
Gene Symbol: prkcz    Nomenclature History

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Previous Names: pkcz (1), si:ch211-150o23.4 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 8 Mapping Details/Browsers
Description: Predicted to have protein serine/threonine kinase activity. Involved in several processes, including animal organ development; photoreceptor cell outer segment organization; and regulation of cell migration involved in sprouting angiogenesis. Is expressed in nervous system and neuroepithelial cell. Orthologous to human PRKCZ (protein kinase C zeta).
Genome Resources: Alliance (1),  Gene:555737 (1),  Ensembl(GRCz11):ENSDARG00000043332 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
dmh19 Point Mutation Unknown Nonsynonymous ENU
la010986Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la016272Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • la026370Tg Transgenic Insertion Unknown Unknown DNA
    la026371Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa12571 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa14706 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa16811 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa21245 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa41168 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • zju205 Complex Unknown Unknown CRISPR
    Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-prkcz 1
    MO1-prkcz N/A 8
    MO2-prkcz N/A 1
    DISEASE ASSOCIATED WITH prkcz HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH prkcz VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process generation of neurons (more)
    Molecular Function ATP binding (more)
    GO Terms (all 20)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA prkcz-201 (1)    Ensembl 1800
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    Name Type Isotype Host Organism Assay Source Publications
    Ab1-prkcz polyclonal IgG Rabbit IHC, WB Santa Cruz Biotechnology, Inc.
    81
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM prkcz No data available
    MARKER RELATIONSHIPS
    prkcz Contained in: [BAC] CH211-113O22 (1), CH211-150O23 (1), DKEY-157O17 (1) (order this)
    prkcz Encodes: [cDNA] MGC:194752 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001030091 (1) 1800 nt
    Genomic GenBank:BX005450 (1) 164218 nt
    Select Tool
    Polypeptide UniProtKB:B0S4T7 (1) 599 aa
    Sequence Information (all 23)
    ORTHOLOGY for prkcz ( Chr: 8 )
    CITATIONS (41)