Gene
pbx1b
- ID
- ZDB-GENE-070424-11
- Name
- pre-B-cell leukemia homeobox 1b
- Symbol
- pbx1b Nomenclature History
- Previous Names
-
- zgc:158824
- Type
- protein_coding_gene
- Location
- Chr: 6 Mapping Details/Browsers
- Description
- Predicted to have DNA-binding transcription activator activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and transcription factor binding activity. Predicted to be involved in animal organ development; neuron development; and positive regulation of transcription by RNA polymerase II. Predicted to localize to nucleus. Is expressed in head. Human ortholog(s) of this gene implicated in B-lymphoblastic leukemia/lymphoma. Orthologous to human PBX1 (PBX homeobox 1).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 2 figures from 2 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| congenital anomalies of kidney and urinary tract syndrome with or without hearing loss, abnormal ears, or developmental delay | Alliance | Congenital anomalies of kidney and urinary tract syndrome with or without hearing loss, abnormal ears, or developmental delay | 617641 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Homeobox, conserved site | Homeobox domain | Homeobox-like domain superfamily |
|---|---|---|---|---|
|
UniProtKB:A2VD48
|
429 | |||
|
UniProtKB:F1QSY5
|
429 |
- Genome Browsers
Interactions and Pathways
No data available
Plasmids
No data available