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ZIRC
ZFIN ID: ZDB-GENE-070209-38
Gene Name: lysine (K)-specific demethylase 4C
Gene Symbol: kdm4c    Nomenclature History

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Previous Names: jmjd2c (1), wu:fd55d07, zgc:153957 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 1 Mapping Details/Browsers
Description: Predicted to have histone demethylase activity (H3-K36 specific) and histone demethylase activity (H3-K9 specific). Involved in blood vessel morphogenesis. Predicted to localize to the histone methyltransferase complex. Human ortholog(s) of this gene implicated in several diseases, including autistic disorder; esophagus squamous cell carcinoma; head and neck cancer; renal cell carcinoma; and withdrawal disorder. Orthologous to human KDM4C (lysine demethylase 4C).
Genome Resources: Alliance (1),  Gene:570194 (1),  Ensembl(GRCz11):ENSDARG00000061504 (1)
GENE EXPRESSION
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa1889 Point Mutation Unknown Splice Site ENU
sa12098 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa19486 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa24842 Point Mutation Unknown Premature Stop ENU
    sa39604 Point Mutation Unknown Premature Stop ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • zko421a Small Deletion Unknown Unknown CRISPR
  • China Zebrafish Resource Center (CZRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    CRISPR1-kdm4c 1
    MO1-kdm4c N/A 2
    PHENOTYPE No data available
    DISEASE ASSOCIATED WITH kdm4c HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH kdm4c VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process blood vessel morphogenesis (more)
    Cellular Component nucleus (more)
    Molecular Function metal ion binding (more)
    GO Terms (all 7)
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA kdm4c-201 (1)    Ensembl 5044
    ncRNA kdm4c-002 (1)    Ensembl 516
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM kdm4c No data available
    MARKER RELATIONSHIPS
    kdm4c Contained in: [BAC] CH73-173K21 (1) (order this)
    kdm4c Encodes: [EST] fd55d07
    [cDNA] MGC:153957 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001083851 (1) 5056 bp
    Genomic GenBank:CU468286 (1) 101210 bp
    Select Tool
    Polypeptide UniProtKB:A2RRT0 (1) 1482 aa
    Sequence Clusters UniGene:17381 (1)
    Sequence Information (all 13)
    ORTHOLOGY for kdm4c ( Chr: 1 )
    CITATIONS (22)