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Gene

kdm4c

ID
ZDB-GENE-070209-38
Name
lysine (K)-specific demethylase 4C
Symbol
kdm4c Nomenclature History
Previous Names
  • jmjd2c (1)
  • wu:fd55d07
  • zgc:153957 (1)
Type
protein_coding_gene
Location
Chr: 1 Mapping Details/Browsers
Description
Predicted to enable histone demethylase activity (H3-K36 specific) and histone demethylase activity (H3-K9 specific). Acts upstream of or within blood vessel morphogenesis. Predicted to be active in nucleus. Is expressed in female organism. Human ortholog(s) of this gene implicated in autistic disorder; breast cancer; carcinoma (multiple); head and neck cancer; and withdrawal disorder. Orthologous to human KDM4C (lysine demethylase 4C).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
1 figure from Newman et al., 2019
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With kdm4c Human Ortholog
No data available
Associated With kdm4c Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001965 Zinc finger, PHD-type
Domain IPR002999 Tudor domain
Domain IPR003347 JmjC domain
Domain IPR003349 JmjN domain
Domain IPR034732 Extended PHD (ePHD) domain
Domain IPR040477 Lysine-specific demethylase 4, Tudor domain
Homologous_superfamily IPR011011 Zinc finger, FYVE/PHD-type
Homologous_superfamily IPR013083 Zinc finger, RING/FYVE/PHD-type
Domain Details Per Protein
Protein Length Extended PHD (ePHD) domain JmjC domain JmjN domain Lysine-specific demethylase 4, Tudor domain Tudor domain Zinc finger, FYVE/PHD-type Zinc finger, PHD-type Zinc finger, RING/FYVE/PHD-type
UniProtKB:A2RRT0 1482
UniProtKB:A0A2R8RU42 1460
UniProtKB:F1QPD2 1482
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations