Gene

ift70

ID
ZDB-GENE-070117-2066
Name
intraflagellar transport 70
Symbol
ift70 Nomenclature History
Previous Names
  • flr (1)
  • IFT70 (1)
  • DYF-1 (1)
Type
protein_coding_gene
Location
Chr: 3 Mapping Details/Browsers
Description
Exhibits tubulin-glycine ligase activity. Involved in several processes, including cilium organization; opsin transport; and protein polyglutamylation. Localizes to axonemal microtubule and motile cilium. Is expressed in Kupffer's vesicle; lateral mesoderm; nervous system; and pronephros. Orthologous to several human genes including TTC30B (tetratricopeptide repeat domain 30B).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
5 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
18 figures from 8 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ift70 Human Ortholog
No data available
Associated With ift70 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Family IPR039941 Tetratricopeptide repeat protein 30
Homologous_superfamily IPR011990 Tetratricopeptide-like helical domain superfamily
Repeat IPR013105 Tetratricopeptide repeat 2
Repeat IPR019734 Tetratricopeptide repeat
Domain Details Per Protein
Protein Length Tetratricopeptide-like helical domain superfamily Tetratricopeptide repeat Tetratricopeptide repeat 2 Tetratricopeptide repeat protein 30
UniProtKB:A7YE96 651
UniProtKB:A0A8M9PR90 575
UniProtKB:A0A8M9P934 645
UniProtKB:A0A8M9PYI9 667
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations