ZFIN ID: ZDB-GENE-070112-182
Gene Name: paired box 1a
Gene Symbol: pax1a    Nomenclature History

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Previous Name: zgc:158781

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 17 Mapping Details/Browsers
Description: Predicted to have DNA binding activity and DNA-binding transcription factor activity. Predicted to be involved in multicellular organism development and regulation of transcription, DNA-templated. Predicted to localize to nucleus. Is expressed in sclerotome. Human ortholog(s) of this gene implicated in branchiootorenal syndrome. Orthologous to human PAX1 (paired box 1).
Genome Resources: Alliance (1),  Gene:564359 (1),  Ensembl(GRCz11):ENSDARG00000008203 (1)
GENE EXPRESSION
All Expression Data: Fig. S9 from Qiu et al., 2016
Wild-type Stages, Structures: Pharyngula:Prim-5 (24.0h-30.0h) to Hatching:Long-pec (48.0h-60.0h)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS No data available
PHENOTYPE No data available
DISEASE ASSOCIATED WITH pax1a HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Otofaciocervical syndrome 2 615560
DISEASE ASSOCIATED WITH pax1a VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process multicellular organism development (more)
Cellular Component nucleus (more)
Molecular Function DNA binding (more)
GO Terms (all 5)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA pax1a-201 (1)    Ensembl 1597
pax1a-202 (1)    Ensembl 976
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM pax1a
Construct Regulatory Regions Coding Sequences Species Tg Lines Publications
Tg(pax1a:GFP) pax1a GFP Danio rerio 1 1
MARKER RELATIONSHIPS
pax1a Contained in: [BAC] DKEY-89L19 (1) (order this)
pax1a Encodes: [cDNA] MGC:158781 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_001080592 (1) 1632 nt
Genomic GenBank:BX927409 (1) 154287 nt
Select Tool
Polypeptide UniProtKB:A1L2C3 (1) 359 aa
Sequence Information (all 11)
ORTHOLOGY for pax1a ( Chr: 17 )
CITATIONS (23)