Gene

esrp1

ID
ZDB-GENE-070112-1732
Name
epithelial splicing regulatory protein 1
Symbol
esrp1 Nomenclature History
Previous Names
  • rbm35a
  • wu:fi28a07
  • zgc:154050
Type
protein_coding_gene
Location
Chr: 16 Mapping Details/Browsers
Description
Predicted to have mRNA binding activity. Predicted to be involved in regulation of RNA splicing. Predicted to localize to nucleoplasm and ribonucleoprotein complex. Is expressed in several structures, including digestive system; ectoderm; epidermis; median fin fold; and tail bud. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 109. Orthologous to human ESRP1 (epithelial splicing regulatory protein 1).
Genome Resources
Note
None
Expression
All Expression Data
3 figures from 2 publications
Cross-Species Comparison
High Throughput Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
Fig. S3 from Burguera et al., 2017
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With esrp1 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
autosomal recessive nonsyndromic deafness 109 Alliance ?Deafness, autosomal recessive 109 618013
Associated With esrp1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR000504 RNA recognition motif domain
Domain IPR013520 Exonuclease, RNase T/DNA polymerase III
Domain IPR034427 ESRP1, RNA recognition motif 1
Homologous_superfamily IPR012337 Ribonuclease H-like superfamily
Homologous_superfamily IPR012677 Nucleotide-binding alpha-beta plait domain superfamily
Homologous_superfamily IPR035979 RNA-binding domain superfamily
Homologous_superfamily IPR036397 Ribonuclease H superfamily
Domain Details Per Protein
Protein Length ESRP1, RNA recognition motif 1 Exonuclease, RNase T/DNA polymerase III Nucleotide-binding alpha-beta plait domain superfamily Ribonuclease H-like superfamily Ribonuclease H superfamily RNA-binding domain superfamily RNA recognition motif domain
UniProtKB:A1L1G1 714
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-esrp1
  • WB
1
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations