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ZIRC
ZFIN ID: ZDB-GENE-061026-3
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Gene Name: nyctalopin
Gene Symbol: nyx    Nomenclature History

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 9 Mapping Details/Browsers
Description: Involved in optokinetic behavior and visual perception. Used to study congenital stationary night blindness and congenital stationary night blindness 1A. Human ortholog(s) of this gene implicated in congenital stationary night blindness 1A and night blindness. Is expressed in retinal ganglion cell layer; retinal inner nuclear layer; retinal inner plexiform layer; and retinal outer plexiform layer. Orthologous to human NYX (nyctalopin).
Genome Resources: Alliance (1),  Gene:568821 (1),  Ensembl(GRCz11):ENSDARG00000061791 (2)
GENE EXPRESSION
All Expression Data: 5 figures from Bahadori et al., 2006
Wild-type Stages, Structures: Larval:Protruding-mouth (72.0h-96.0h, 3.5mm) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa31731 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
    • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-nyx N/A 2
    PHENOTYPE
    Data: Fig. 4 from Peachey et al., 2012
    Observed in:
    DISEASE ASSOCIATED WITH nyx HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    congenital stationary night blindness 1A Alliance Night blindness, congenital stationary (complete), 1A, X-linked 310500
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process optokinetic behavior (more)
    GO Terms (all 2)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000483 (1)
  • InterPro:IPR001611 (1)
  • InterPro:IPR003591 (1)
  • InterPro:IPR032675 (1)
  • PROSITE:PS51450 (1)
  • Pfam:PF13855 (1)
    • TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA nyx-201 (1)    Ensembl 2226
    Select Tool
    Browsers: UCSC,  NCBI,  Ensembl,  ZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM nyx
    Construct Regulatory Regions Coding Sequences Species Tg Lines Publications
    Tg(nyx:GAL4-VP16) nyx GAL4,  VP16 Danio rerio 1 16
    MARKER RELATIONSHIPS
    nyx Contained in: [BAC] DKEY-216E24 (1) (order this)
    nyx Encodes: [cDNA] MGC:194863 (1) (order this), MGC:194882 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001077617 (1) 1410 bp
    Select Tool
    Genomic GenBank:BX545856 (1) 209295 bp Blast at MegaBLAST
    Polypeptide UniProtKB:Q00P20 (1) 469 aa
    Select Tool
    Sequence Clusters UniGene:82636 (1)
    Sequence Information (all 17)
    ORTHOLOGY for nyx ( Chr: 9 )
    CITATIONS (19)