ZFIN ID: ZDB-GENE-061026-3 |
Gene Name: | nyctalopin | ||||||
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Gene Symbol: | nyx Nomenclature History | ||||||
Previous Name: | |||||||
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Gene Type: | protein_coding_gene | ||||||
Location: | Chr: 9 Mapping Details/Browsers | ||||||
Description: | Involved in optokinetic behavior and visual perception. Used to study congenital stationary night blindness and congenital stationary night blindness 1A. Human ortholog(s) of this gene implicated in congenital stationary night blindness 1A and night blindness. Is expressed in retinal ganglion cell layer; retinal inner nuclear layer; retinal inner plexiform layer; and retinal outer plexiform layer. Orthologous to human NYX (nyctalopin). | ||||||
Genome Resources: | Alliance (1), Gene:568821 (1), Ensembl(GRCz11):ENSDARG00000061791 (2) |
All Expression Data: | 5 figures from Bahadori et al., 2006 |
Wild-type Stages, Structures: | Larval:Protruding-mouth (72.0h-96.0h, 3.5mm) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth) |
Allele | Type | Localization | Consequence | Mutagen | Suppliers |
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sa31731 | Point Mutation | Unknown | Premature Stop | ENU |
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Data: | Fig. 4 from Peachey et al., 2012 |
Observed in: |
Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
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congenital stationary night blindness 1A | Alliance | Night blindness, congenital stationary (complete), 1A, X-linked | 310500 |
Human Disease | Fish | Conditions | Citations |
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congenital stationary night blindness | WT + MO1-nyx | standard conditions | Bahadori et al., 2006 |
congenital stationary night blindness 1A | WT + MO1-nyx | standard conditions | Peachey et al., 2012 |
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Type | Name | Length (nt) | Analysis | |
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mRNA |
nyx-201
(1)
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2226 |
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Browsers: UCSC, NCBI, Ensembl, ZFIN |
Construct | Regulatory Regions | Coding Sequences | Species | Tg Lines | Publications |
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Tg(nyx:GAL4-VP16) | nyx | GAL4, VP16 | Danio rerio | 1 | 16 |
nyx Contained in: | [BAC] DKEY-216E24 (1) (order this) |
nyx Encodes: | [cDNA] MGC:194863 (1) (order this), MGC:194882 (1) (order this) |
Type | Accession # | Length (bp/aa) | Analysis |
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RNA | RefSeq:NM_001077617 (1) | 1410 bp |
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Genomic | GenBank:BX545856 (1) | 209295 bp | Blast at MegaBLAST |
Polypeptide | UniProtKB:Q00P20 (1) | 469 aa |
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Sequence Clusters | UniGene:82636 (1) |