ZFIN ID: ZDB-GENE-061013-323
Gene Name: serine peptidase inhibitor, Kunitz type, 2
Gene Symbol: spint2    Nomenclature History

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Previous Names: fb52h04, fe24a06, wu:fb52h04, wu:fe24a06, zgc:153795

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 15 Mapping Details/Browsers
Description: Predicted to have serine-type endopeptidase inhibitor activity. Predicted to localize to extracellular space. Is expressed in liver. Human ortholog(s) of this gene implicated in congenital secretory sodium diarrhea 3. Orthologous to human SPINT2 (serine peptidase inhibitor, Kunitz type 2).
Genome Resources: Alliance (1),  Gene:562009 (1),  Ensembl(GRCz11):ENSDARG00000069476 (1)
GENE EXPRESSION
All Expression Data: Fig. S3 from Wang et al., 2017
Wild-type Stages, Structures: Adult (90d-730d, breeding adult) to Adult (90d-730d, breeding adult)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa6371 Point Mutation Unknown Premature Stop ENU
PHENOTYPE No data available
DISEASE ASSOCIATED WITH spint2 HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
congenital secretory sodium diarrhea 3 Alliance Diarrhea 3, secretory sodium, congenital, syndromic 270420
DISEASE ASSOCIATED WITH spint2 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Cellular Component integral component of membrane (more)
Molecular Function serine-type endopeptidase inhibitor activity (more)
GO Terms (all 4)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA spint2-201 (1)    Ensembl 2024
spint2-202 (1)    Ensembl 836
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM spint2 No data available
MARKER RELATIONSHIPS
spint2 Contained in: [BAC] CH211-51K14 (1)
spint2 Encodes: [EST] fb52h04, fe24a06
[cDNA] MGC:153795 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_001077250 (1) 1994 nt
Genomic GenBank:AL928724 (1) 165299 nt
Select Tool
Polypeptide UniProtKB:F1QEV7 (1) 431 aa
Sequence Information (all 20)
ORTHOLOGY for spint2 ( Chr: 15 )
CITATIONS (21)