Research
General Information
ZIRC
ZFIN ID: ZDB-GENE-060803-1
Gene Name: Abelson helper integration site 1
Gene Symbol: ahi1
Previous Name: ZAhi-1 (1)
Location: Chr: 17   Details
Nomenclature History
GENE EXPRESSION
All Expression Data: 5 figures from 3 publications
Wild-type Stages, Structures: Segmentation:5-9 somites (11.66h-14.0h) to Adult (90d-730d, breeding adult)
  brain, cerebellum, forebrain, heart (all 23) expand
Curated Microarray Expression: GEO (1)
MUTANTS AND TARGETED KNOCKDOWNS
Alleles: sa15936
Knockdown reagents: MO1-ahi1 (1), MO2-ahi1 (1)
PHENOTYPE
Data: 4 figures from Simms et al., 2012
Observed in: brain, camera-type eye morphogenesis, ciliated epithelial cell cilium, eye (all 14) expand

Phenotype of Human Orthologue OMIM Phenotype ID
Joubert syndrome-3 608629
GENE ONTOLOGY
Ontology GO Term
Biological Process determination of left/right symmetry (more)
Cellular Component cellular_component (more)
Molecular Function molecular_function (more)
GO Terms (all 4)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001452 (1)
  • InterPro:IPR001680 (1)
  • InterPro:IPR015943 (1)
  • InterPro:IPR017986 (1)
  • InterPro:IPR019775 (1)
  • PROSITE:PS00678 (1)
  • PROSITE:PS50002 (1)
  • PROSITE:PS50082 (1)
  • PROSITE:PS50294 (1)
  • Pfam:PF00018 (1)
  • Pfam:PF00400 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA ahi1-001 (1) 3955
    ahi1-002 (1) 3686
    ncRNA ahi1-003 (1) 545
    GENE PRODUCT DESCRIPTION
    ANTIBODIES No data available
    CONSTRUCTS WITH SEQUENCES FROM ahi1 No data available
    SEGMENT (CLONE AND PROBE) RELATIONSHIPS
    ahi1 Contained in: [BAC] CH211-195G8 (1) (order this), CH211-236P5 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001077561 (1) 3221 bp
    Genomic GenBank:BX248131 (1) 162685 bp
    Select Tool
    Polypeptide UniProtKB:F8W3V6 (1) 1193 aa
    Sequence Clusters UniGene:74685 (1)
    Sequence Information (all 16)
    OTHER ahi1 GENE PAGES
  • Gene:562701 (1)
  • VEGA:OTTDARG00000035059 (1)
  • Ensembl(Zv9):ENSDARG00000044056 (1)
  • ORTHOLOGY
      Evidence
    Species Symbol Chr (Position) Accession # AA
    Zebrafish ahi1 17  
    Human AHI1 6 (6q23.3)
  • OMIM:608894
  • Gene:54806
  • Mouse Ahi1 10 ( 9.75 cM)
  • MGI:87971
  • Gene:52906
  • Orthology Details
    CITATIONS (11)