Gene

dab1a

ID
ZDB-GENE-060528-1
Name
DAB adaptor protein 1a
Symbol
dab1a Nomenclature History
Previous Names
  • dab1
  • si:dkey-242m13.1
Type
protein_coding_gene
Location
Chr: 20 Mapping Details/Browsers
Description
Predicted to be involved in lateral motor column neuron migration and ventral spinal cord development. Predicted to localize to cytoplasm. Human ortholog(s) of this gene implicated in spinocerebellar ataxia type 37. Is expressed in several structures, including brain; immature eye; pronephric duct; retina; and spinal cord interneuron. Orthologous to human DAB1 (DAB adaptor protein 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
10 figures from 4 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
5 figures from 3 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With dab1a Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Spinocerebellar ataxia 37 615945
Associated With dab1a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Conserved_site IPR048559 Disabled homolog 1/2, sulfatide-binding motif
Domain IPR006020 PTB/PI domain
Domain IPR048561 Disabled, phosphotyrosine-binding domain
Homologous_superfamily IPR011993 PH-like domain superfamily
Domain Details Per Protein
Protein Length Disabled homolog 1/2, sulfatide-binding motif Disabled, phosphotyrosine-binding domain PH-like domain superfamily PTB/PI domain
UniProtKB:A0A8M3AKN7 571
UniProtKB:A0A8M3AW18 597
UniProtKB:A0A8M2BHH7 576
UniProtKB:F1Q6J4 565
UniProtKB:A2BEF7 537
UniProtKB:A0A8M3B3Y8 563
UniProtKB:Q1PSH4 588
UniProtKB:A0A0R4IQY1 586
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations