Gene

sec14l8

ID
ZDB-GENE-060526-180
Name
SEC14-like lipid binding 8
Symbol
sec14l8 Nomenclature History
Previous Names
  • si:ch211-89f7.1
Type
protein_coding_gene
Location
Chr: 5 Mapping Details/Browsers
Description
Enables GTP binding activity; GTPase activating protein binding activity; and GTPase activity. Acts upstream of or within with a positive effect on angioblast cell migration from lateral mesoderm to midline. Acts upstream of or within Wnt signaling pathway, calcium modulating pathway; positive regulation of epiboly involved in gastrulation with mouth forming second; and regulation of convergent extension involved in axis elongation. Is extrinsic component of plasma membrane. Is expressed in blastomere; posterior cardinal vein; trunk vasculature; vascular cord; and vasculature. Orthologous to several human genes including SEC14L2 (SEC14 like lipid binding 2) and SEC14L3 (SEC14 like lipid binding 3).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
3 figures from 2 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
5 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With sec14l8 Human Ortholog
No data available
Associated With sec14l8 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001251 CRAL-TRIO lipid binding domain
Domain IPR009038 GOLD domain
Domain IPR011074 CRAL/TRIO, N-terminal domain
Homologous_superfamily IPR036273 CRAL/TRIO, N-terminal domain superfamily
Homologous_superfamily IPR036598 GOLD domain superfamily
Homologous_superfamily IPR036865 CRAL-TRIO lipid binding domain superfamily
Domain Details Per Protein
Protein Length CRAL-TRIO lipid binding domain CRAL-TRIO lipid binding domain superfamily CRAL/TRIO, N-terminal domain CRAL/TRIO, N-terminal domain superfamily GOLD domain GOLD domain superfamily
UniProtKB:A2BIR0 395
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations