Gene

atxn1a

ID

ZDB-GENE-060503-759

Name

ataxin 1a

Symbol

atxn1a Nomenclature History

Previous Names

atxn1b (1)
si:ch211-125a6.1 (1)

Type

protein_coding_gene

Location

Chr: 19 Mapping Details/Browsers

Description

Predicted to have DNA binding activity and RNA binding activity. Predicted to be involved in negative regulation of transcription by RNA polymerase II and nervous system development. Localizes to nucleus. Is expressed in cerebellum. Human ortholog(s) of this gene implicated in spinocerebellar ataxia type 1. Orthologous to human ATXN1 (ataxin 1).

Genome Resources

Note

None

Comparative Information

Expression

All Expression Data

5 figures from 3 publications

Cross-Species Comparison

High Throughput Data

Expression Atlas

Thisse Expression Data

Wild Type Expression Summary

Phenotype

All Phenotype Data: No data available
Cross-Species Comparison: Alliance

Phenotype Summary

Mutations

Mutants

Sequence Targeting Reagents

Human Disease

Associated With atxn1a Human Ortholog

Disease Ontology Term	Multi-Species Data	OMIM Term	OMIM Phenotype ID
spinocerebellar ataxia type 1	Alliance	Spinocerebellar ataxia 1	164400

Associated With atxn1a Via Experimental Models

No data available

Gene Ontology

Protein Domains

Domain, Family, and Site Summary

Type	InterPro ID	Name
Domain	IPR003652	Ataxin, AXH domain
Domain	IPR020997	Capicua transcriptional repressor modulator, Ataxin-1
Family	IPR040172	Ataxin-1
Family	IPR043404	ATAXIN1-like
Homologous_superfamily	IPR036096	Ataxin, AXH domain superfamily