Gene

exosc5

ID
ZDB-GENE-060503-675
Name
exosome component 5
Symbol
exosc5 Nomenclature History
Previous Names
  • si:ch211-194n6.2
  • zgc:153707
Type
protein_coding_gene
Location
Chr: 18 Mapping Details/Browsers
Description
Involved in RNA metabolic process. Predicted to be part of cytoplasmic exosome (RNase complex) and nuclear exosome (RNase complex). Orthologous to human EXOSC5 (exosome component 5).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from Slavotinek et al., 2020
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With exosc5 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Cerebellar ataxia, brain abnormalities, and cardiac conduction defects 619576
Associated With exosc5 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001247 Exoribonuclease, phosphorolytic domain 1
Domain IPR015847 Exoribonuclease, phosphorolytic domain 2
Homologous_superfamily IPR020568 Ribosomal protein S5 domain 2-type fold
Homologous_superfamily IPR027408 PNPase/RNase PH domain superfamily
Homologous_superfamily IPR036345 Exoribonuclease, PH domain 2 superfamily
Domain Details Per Protein
Protein Length Exoribonuclease, PH domain 2 superfamily Exoribonuclease, phosphorolytic domain 1 Exoribonuclease, phosphorolytic domain 2 PNPase/RNase PH domain superfamily Ribosomal protein S5 domain 2-type fold
UniProtKB:Q0P3Y3 218
UniProtKB:Q1LVM3 222
UniProtKB:Q1LVM4 128
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations