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Gene

ptprfb

ID
ZDB-GENE-060503-530
Name
protein tyrosine phosphatase receptor type Fb
Symbol
ptprfb Nomenclature History
Previous Names
  • lar (1)
  • fj23e12
  • si:dkey-21k10.1
  • wu:fj23e12 (1)
Type
protein_coding_gene
Location
Chr: 2 Mapping Details/Browsers
Description
Predicted to enable protein tyrosine phosphatase activity. Acts upstream of or within sensory neuron axon guidance. Predicted to be located in membrane. Predicted to be integral component of membrane. Is expressed in liver and nervous system. Human ortholog(s) of this gene implicated in hyperinsulinism. Orthologous to human PTPRF (protein tyrosine phosphatase receptor type F).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
3 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ptprfb Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
?Breasts and/or nipples, aplasia or hypoplasia of, 2 616001
Associated With ptprfb Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR016130 Protein-tyrosine phosphatase, active site
Domain IPR000242 PTP type protein phosphatase
Domain IPR000387 Tyrosine specific protein phosphatases domain
Domain IPR003595 Protein-tyrosine phosphatase, catalytic
Domain IPR003598 Immunoglobulin subtype 2
Domain IPR003599 Immunoglobulin subtype
Domain IPR003961 Fibronectin type III
Domain IPR007110 Immunoglobulin-like domain
Domain IPR013098 Immunoglobulin I-set
Homologous_superfamily IPR013783 Immunoglobulin-like fold
Homologous_superfamily IPR029021 Protein-tyrosine phosphatase-like
Homologous_superfamily IPR036116 Fibronectin type III superfamily
Homologous_superfamily IPR036179 Immunoglobulin-like domain superfamily
Domain Details Per Protein
Protein Length Fibronectin type III Fibronectin type III superfamily Immunoglobulin I-set Immunoglobulin-like domain Immunoglobulin-like domain superfamily Immunoglobulin-like fold Immunoglobulin subtype Immunoglobulin subtype 2 Protein-tyrosine phosphatase, active site Protein-tyrosine phosphatase, catalytic Protein-tyrosine phosphatase-like PTP type protein phosphatase Tyrosine specific protein phosphatases domain
UniProtKB:A0A2R8QDC8 1913
UniProtKB:C7U152 96
UniProtKB:F1RAP4 147
UniProtKB:A0A2R8QPM2 1906
UniProtKB:A4IFW2 1909
UniProtKB:A0A2R8QMX8 1915
UniProtKB:A0A0R4IGS0 1884
UniProtKB:A0A2R8QMX7 1798
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations