Gene

ptprfb

ID
ZDB-GENE-060503-530
Name
protein tyrosine phosphatase receptor type Fb
Symbol
ptprfb Nomenclature History
Previous Names
  • lar (1)
  • fj23e12
  • si:dkey-21k10.1
  • wu:fj23e12 (1)
Type
protein_coding_gene
Location
Chr: 2 Mapping Details/Browsers
Description
Predicted to enable protein tyrosine phosphatase activity. Acts upstream of or within sensory neuron axon guidance. Predicted to be located in plasma membrane. Is expressed in liver and nervous system. Human ortholog(s) of this gene implicated in hyperinsulinism. Orthologous to human PTPRF (protein tyrosine phosphatase receptor type F).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
3 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
2 figures from 2 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With ptprfb Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
?Breasts and/or nipples, aplasia or hypoplasia of, 2 616001
Associated With ptprfb Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Active_site IPR016130 Protein-tyrosine phosphatase, active site
Domain IPR000242 Tyrosine-specific protein phosphatase, PTPase domain
Domain IPR000387 Tyrosine-specific protein phosphatases domain
Domain IPR003595 Protein-tyrosine phosphatase, catalytic
Domain IPR003598 Immunoglobulin subtype 2
Domain IPR003599 Immunoglobulin domain subtype
Domain IPR003961 Fibronectin type III
Domain IPR007110 Immunoglobulin-like domain
Domain IPR013098 Immunoglobulin I-set
Family IPR050713 Receptor-type Tyrosine-protein Phosphatases/Ushers
Homologous_superfamily IPR013783 Immunoglobulin-like fold
Homologous_superfamily IPR029021 Protein-tyrosine phosphatase-like
Homologous_superfamily IPR036116 Fibronectin type III superfamily
Homologous_superfamily IPR036179 Immunoglobulin-like domain superfamily
Domain Details Per Protein
Protein Additional Resources Length Fibronectin type III Fibronectin type III superfamily Immunoglobulin domain subtype Immunoglobulin I-set Immunoglobulin-like domain Immunoglobulin-like domain superfamily Immunoglobulin-like fold Immunoglobulin subtype 2 Protein-tyrosine phosphatase, active site Protein-tyrosine phosphatase, catalytic Protein-tyrosine phosphatase-like Receptor-type Tyrosine-protein Phosphatases/Ushers Tyrosine-specific protein phosphatase, PTPase domain Tyrosine-specific protein phosphatases domain
UniProtKB:A0A8M3APM3 InterPro 1904
UniProtKB:A0A8M3B069 InterPro 1918
UniProtKB:A0A8M3AQ61 InterPro 1825
UniProtKB:A0A8M9QC31 InterPro 1807
UniProtKB:A0A8M3B7N0 InterPro 1900
UniProtKB:A0A8M3B074 InterPro 1802
UniProtKB:A0A8M3B7M8 InterPro 1921
UniProtKB:A0A2R8QDC8 InterPro 1913
UniProtKB:A0A8M3AQ53 InterPro 1927
UniProtKB:A0A8M3AQ56 InterPro 1919
UniProtKB:A0A8M3AX63 InterPro 1923
UniProtKB:A0A8M9Q0G3 InterPro 1817
UniProtKB:A0A8M3APL8 InterPro 1923
UniProtKB:A0A8M9QPW8 InterPro 1798
UniProtKB:A4IFW2 InterPro 1909
UniProtKB:A0A8M9QH96 InterPro 1917
UniProtKB:A0A8M9QLG3 InterPro 1813
UniProtKB:A0A8M9QC27 InterPro 1811
Transcripts
Genome Browsers
Type Name Annotation Method Has Havana Data Length (nt) Analysis
mRNA ptprfb-201 (1) Ensembl 7,679 nt
mRNA ptprfb-202 (1) Ensembl 442 nt
mRNA ptprfb-204 (1) Ensembl 7,327 nt
mRNA ptprfb-205 (1) Ensembl 7,957 nt
mRNA ptprfb-206 (1) Ensembl 7,978 nt
mRNA ptprfb-207 (1) Ensembl 7,984 nt
mRNA ptprfb-208 (1) Ensembl 7,633 nt
ncRNA ptprfb-003 (1) Ensembl 524 nt
Interactions and Pathways
No data available
Antibodies
No data available
Plasmids
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations