ZFIN ID: ZDB-GENE-060503-530
Gene Name: protein tyrosine phosphatase receptor type Fb
Gene Symbol: ptprfb    Nomenclature History

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Previous Names: lar (1), fj23e12, si:dkey-21k10.1, wu:fj23e12 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 2 Mapping Details/Browsers
Description: Predicted to have protein tyrosine phosphatase activity. Involved in sensory neuron axon guidance. Predicted to localize to integral component of membrane. Is expressed in liver and nervous system. Human ortholog(s) of this gene implicated in hyperinsulinism. Orthologous to human PTPRF (protein tyrosine phosphatase receptor type F).
Genome Resources: Alliance (1),  Gene:799867 (1),  Ensembl(GRCz11):ENSDARG00000005754 (2)
GENE EXPRESSION
All Expression Data: 3 figures from 3 publications
Wild-type Stages, Structures: Pharyngula:Prim-5 (24.0h-30.0h) to Adult (90d-730d, breeding adult)
 
High Throughput Expression: GEO (1) , Expression Atlas (1)
DISEASE ASSOCIATED WITH ptprfb HUMAN ORTHOLOG
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
?Breasts and/or nipples, aplasia or hypoplasia of, 2 616001
DISEASE ASSOCIATED WITH ptprfb VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process sensory neuron axon guidance (more)
Cellular Component integral component of membrane (more)
Molecular Function heparin binding (more)
GO Terms (all 13)
PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
TRANSCRIPTS
Type Name Length (nt) Analysis
mRNA ptprfb-201 (1)    Ensembl 7679
ptprfb-202 (1)    Ensembl 442
ncRNA ptprfb-003 (1)    Ensembl 524
Browsers: UCSCNCBIEnsemblZFIN
INTERACTIONS AND PATHWAYS
ANTIBODIES No data available
PLASMIDS No data available
CONSTRUCTS WITH SEQUENCES FROM ptprfb No data available
MARKER RELATIONSHIPS
ptprfb Contained in: [BAC] CH211-113D14 (1), DKEY-21K10 (1) (order this), DKEY-179M13 (1) (order this), DKEY-183G16 (1) (order this)
ptprfb Contains: [SNP] rs3727616 (1), rs3727617 (1)
ptprfb Encodes: [EST] fj23e12
[cDNA] MGC:154028 (1)
SEQUENCE INFORMATION
Type Accession # Length (nt/aa) Analysis
RNA RefSeq:NM_001083576 (1) 7718 nt
Genomic GenBank:BX248089 (1) 247834 nt Blast at MegaBLAST
Polypeptide UniProtKB:A0A2R8QMX8 (1) 1915 aa
Sequence Information (all 62)
ORTHOLOGY for ptprfb ( Chr: 2 )
CITATIONS (32)