Gene
slc17a8
- ID
- ZDB-GENE-060503-416
- Name
- solute carrier family 17 member 8
- Symbol
- slc17a8 Nomenclature History
- Previous Names
- Type
- protein_coding_gene
- Location
- Chr: 18 Mapping Details/Browsers
- Description
- Predicted to have L-glutamate transmembrane transporter activity. Involved in equilibrioception; regulation of synapse structure or activity; and vestibular reflex. Predicted to localize to excitatory synapse and integral component of synaptic vesicle membrane. Human ortholog(s) of this gene implicated in autosomal dominant nonsyndromic deafness 25. Is expressed in hair cell; hair cell anterior macula; inner ear; neuromast; and neuromast hair cell. Orthologous to human SLC17A8 (solute carrier family 17 member 8).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 8 figures from 4 publications
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
- No data available
Wild Type Expression Summary
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| autosomal dominant nonsyndromic deafness 25 | Alliance | Deafness, autosomal dominant 25 | 605583 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | Major facilitator superfamily | Major facilitator superfamily domain | Major Facilitator Superfamily Sodium/Anion Cotransporter | MFS transporter superfamily |
|---|---|---|---|---|---|
|
UniProtKB:Q1L8X9
|
590 |
| Type | Name | Annotation Method | Has Havana Data | Length (nt) | Analysis |
|---|---|---|---|---|---|
| mRNA |
slc17a8-201
(1)
|
Ensembl | 1,773 nt |
Interactions and Pathways
No data available
| Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
|---|---|---|---|---|---|---|---|
| Ab1-slc17a8 | polyclonal | Rabbit |
|
8 |
Plasmids
No data available