ZFIN ID: ZDB-GENE-060312-35
Gene Name: RNA-binding region (RNP1, RRM) containing 3
Gene Symbol: rnpc3    Nomenclature History

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Previous Names: caliban (1), clbn, zgc:136847 (1)

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 24 Mapping Details/Browsers
Description: Predicted to have U12 snRNA binding activity and pre-mRNA intronic binding activity. Involved in animal organ development; digestive tract development; and mRNA splicing, via spliceosome. Predicted to localize to U12-type spliceosomal complex. Is expressed in digestive system; pharyngeal arch; post-vent region; proliferative region; and sensory system. Human ortholog(s) of this gene implicated in isolated growth hormone deficiency. Orthologous to human RNPC3 (RNA binding region (RNP1, RRM) containing 3).
Genome Resources: Alliance (1),  Gene:565672 (1),  Ensembl(GRCz11):ENSDARG00000011247 (2)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
la028632Tg Transgenic Insertion Unknown Unknown DNA
  • Zebrafish International Resource Center (ZIRC) (order this)
  • s846 Point Mutation Unknown Cryptic Acceptor Splice Site ENU
    sa37916 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • zm00416857Tg Transgenic Insertion Intron 1 Unknown DNA
    DISEASE ASSOCIATED WITH rnpc3 HUMAN ORTHOLOG
    Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
    ?Growth hormone deficiency, isolated, type V 618160
    DISEASE ASSOCIATED WITH rnpc3 VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process digestive tract development (more)
    Cellular Component nucleus (more)
    Molecular Function nucleic acid binding (more)
    GO Terms (all 13)
    PROTEIN FAMILIES, DOMAINS AND SITES No links to external sites available
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA rnpc3-201 (1)    Ensembl 1729
    rnpc3-202 (1)    Ensembl 897
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES No data available
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM rnpc3 No data available
    MARKER RELATIONSHIPS
    rnpc3 Contained in: [BAC] CH73-178J6 (1), CH211-287N14 (1)
    rnpc3 Encodes: [cDNA] MGC:136847 (1)
    SEQUENCE INFORMATION
    Type Accession # Length (nt/aa) Analysis
    RNA RefSeq:NM_001039930 (1) 1722 nt
    Genomic GenBank:CR388050 (1) 176933 nt
    Select Tool
    Polypeptide UniProtKB:F1Q8J0 (1) 505 aa
    Sequence Information (all 20)
    ORTHOLOGY for rnpc3 ( Chr: 24 )
    CITATIONS (31)