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ZIRC
ZFIN ID: ZDB-GENE-060228-2
Gene Name: ligand of numb-protein X 2a
Gene Symbol: lnx2a    Nomenclature History

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Previous Name: lnx2

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(Including Attributions)
Gene Type: protein_coding_gene
Location: Chr: 24 Mapping Details/Browsers
Description: Exhibits ubiquitin protein ligase activity. Involved in exocrine pancreas development. Is expressed in central nervous system; endoderm; and pancreatic system. Orthologous to human LNX2 (ligand of numb-protein X 2).
Genome Resources: Alliance (1),  Gene:553331 (1),  Ensembl(GRCz11):ENSDARG00000029177 (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa24496 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa24497 Point Mutation Unknown Premature Stop ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa37882 Point Mutation Unknown Splice Site ENU
  • European Zebrafish Resource Center (EZRC) (order this)
  • Zebrafish International Resource Center (ZIRC) (order this)
  • y447 Small Deletion Donor Splice Site of Exon 2 Unknown TALEN
  • Zebrafish International Resource Center (ZIRC) (order this)
  • y448 Small Deletion Unknown Frameshift, Premature Stop TALEN
  • Zebrafish International Resource Center (ZIRC) (order this)
  • Sequence Targeting Reagents
    Targeting Reagent Created Alleles Publications
    MO1-lnx2a N/A 1
    TALEN1-lnx2a 3
    DISEASE ASSOCIATED WITH lnx2a HUMAN ORTHOLOG No data available
    DISEASE ASSOCIATED WITH lnx2a VIA EXPERIMENTAL MODELS No data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process exocrine pancreas development (more)
    Molecular Function ubiquitin protein ligase activity (more)
    GO Terms (all 3)
    TRANSCRIPTS
    Type Name Length (nt) Analysis
    mRNA lnx2a-202 (1)    Ensembl 2726
    Browsers: UCSCNCBIEnsemblZFIN
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    Name Type Isotype Host Organism Assay Source Publications
    Ab1-lnx2a polyclonal Rabbit 1
    PLASMIDS No data available
    CONSTRUCTS WITH SEQUENCES FROM lnx2a No data available
    MARKER RELATIONSHIPS
    lnx2a Contained in: [BAC] CH211-140B10 (1) (order this)
    lnx2a Encodes: [cDNA] MGC:162313 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001113225 (1) 2856 bp
    Genomic GenBank:BX571696 (1) 171175 bp
    Select Tool
    Polypeptide UniProtKB:B6DRF5 (1) 737 aa
    Sequence Clusters UniGene:82850 (1)
    Sequence Information (all 25)
    ORTHOLOGY for lnx2a ( Chr: 24 )
    CITATIONS (18)