ZFIN Gene: lman1

ZFIN ID: ZDB-GENE-060201-4

ZFIN ID: ZDB-GENE-060201-4

Gene Name:

lectin, mannose-binding, 1

Gene Symbol:

lman1

Sequence Ontology ID :

SO:0000704

Previous Names:

fc54c09, fi36e01, wu:fc54c09, wu:fi36e01

Location:

Chr: 21 Mapping Details/Browsers

Nomenclature History

AUTOMATED DESCRIPTION

Predicted to have mannose binding activity. Involved in cellular response to estrogen stimulus. Predicted to localize to the cytoplasm. Human ortholog(s) of this gene implicated in factor V ...

GENE EXPRESSION
All Expression Data:	22 figures from 4 publications
Directly Submitted Expression Data:	6 figures (12 images) from Rauch et al., 2003 [fc54c09]
	7 figures (14 images) from Thisse et al., 2004 [IMAGE:7143659]
	7 figures (13 images) from Thisse et al., 2004 [IMAGE:7147380]
Wild-type Stages, Structures:	Gastrula:50%-epiboly (5.25h-5.66h) to Larval:Days 7-13 (168.0h-14d, 4.5mm, 8 teeth)
	axis diencephalon floor plate hatching gland head immature eye notochord optic primordium optic vesicle otic vesicle pancreas pharyngeal arch pharyngeal arch 3-7 skeleton polster somite unspecified
Curated Microarray Expression:	GEO (1)

MUTATIONS AND SEQUENCE TARGETING REAGENTS

Allele	Type	Localization	Consequence	Mutagen	Suppliers
sa13208	Point Mutation	Unknown	Premature Stop	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)
sa16718	Point Mutation	Unknown	Premature Stop	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)
sa37243	Point Mutation	Unknown	Splice Site	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)
sa43588	Point Mutation	Unknown	Premature Stop	ENU	European Zebrafish Resource Center (EZRC) (order this) Zebrafish International Resource Center (ZIRC) (order this)

PHENOTYPE No data available

DISEASE ASSOCIATED WITH lman1 HUMAN ORTHOLOG

Disease Ontology Term	OMIM Term	OMIM Phenotype ID
	Combined factor V and VIII deficiency	227300

DISEASE ASSOCIATED WITH lman1 VIA EXPERIMENTAL MODELS No data available

GENE ONTOLOGY

Ontology	GO Term
Biological Process	cellular response to estrogen stimulus (more)
Cellular Component	integral component of membrane (more)
Molecular Function	mannose binding (more)

GO Terms (all 11)

PROTEIN FAMILIES, DOMAINS AND SITES
InterPro:IPR005052 (1) InterPro:IPR013320 (1) InterPro:IPR033085 (1)	PROSITE:PS51328 (1)	Pfam:PF03388 (1)

TRANSCRIPTS
Type	Name	Length (bp)	Analysis
mRNA	lman1-201 (1)	2104	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT
	lman1-202 (1)	300	Select Tool ZFIN BLAST NCBI BLAST Ensembl UCSC BLAT

GENE PRODUCT DESCRIPTION No description available

INTERACTIONS AND PATHWAYS

ANTIBODIESNo data available

PLASMIDSNo data available

CONSTRUCTS WITH SEQUENCES FROM lman1 No data available

MARKER RELATIONSHIPS

lman1Contained in:	[BAC] CH73-306K8 (1) (order this), CH211-233A1 (1) (order this)
lman1Contains:	[SNP] rs3729079 (1), rs3729080 (1), rs3729081 (1), rs3729082 (1), rs3729083 (1), rs3729084 (1), rs3729085 (1)
lman1Encodes:	[EST] fc54c09 (order this), fi36e01, IMAGE:7143659 (1) (order this), IMAGE:7147380 (1) (order this)

SEQUENCE INFORMATION

Type	Accession #	Length (bp/aa)	Analysis
RNA	RefSeq:XM_683569 (1)		Select Tool ZFIN BLAST NCBI BLAST MegaBLAST Ensembl UCSC BLAT
Genomic	GenBank:BX248399 (1)	158884bp	Select Tool MegaBLAST Ensembl
Polypeptide	UniProtKB:A0A2R8Q848 (1)	577aa	Select Tool ZFIN BLAST SIB BLAST Ensembl Protein Blast
Sequence Clusters	UniGene:79017 (1)

Sequence Information (all 37)

OTHER lman1 GENE PAGES

Alliance (1)

Gene:559775 (1)

VEGA:OTTDARG00000018936 (1)

Ensembl(GRCz11):ENSDARG00000069980 (2)

ORTHOLOGY for lman1 (Chr: 21)

CITATIONS (27)

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