ZFIN ID: ZDB-GENE-051101-1
Gene Name: WW domain containing transcription regulator 1
Gene Symbol: wwtr1
Sequence Ontology ID : SO:0000704

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Previous Name: taz (1)

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(Including Attributions)
Location: Chr: 22 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Involved in several processes, including animal organ development, epithelial cell fate commitment, and negative regulation of retinoic acid receptor signaling pathway; orthologous to human WWTR1 (WW  ...
GENE EXPRESSION
All Expression Data: 8 figures from 6 publications
Wild-type Stages, Structures: Cleavage:8-cell (1.25h-1.5h) to Larval:Day 5 (120.0h-144.0h, 3.9mm, 6 teeth)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
bns35 Insertion Exon 2 Frameshift, Premature Stop CRISPR
fu55 Complex Unknown Unknown TALEN
mw49 Small Deletion Unknown Frameshift, Premature Stop TALEN
ncv114 Small Deletion Exon 1 Premature Stop TALEN
swu46 Small Deletion Exon 1 Unknown CRISPR
swu47 Small Deletion Exon 1 Unknown CRISPR
Targeting reagents:
PHENOTYPE
Data: 15 figures from 6 publications
Observed in:
DISEASE ASSOCIATED WITH wwtr1 HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH wwtr1 VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process retinal pigment epithelium development (more)
GO Terms (all 7)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR001202 (1)
  • InterPro:IPR036020 (1)
  • PROSITE:PS01159 (1)
  • PROSITE:PS50020 (1)
  • Pfam:PF00397 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA wwtr1-001 (1) 1782
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM wwtr1
    MARKER RELATIONSHIPS
    wwtr1Contained in: [BAC] CH73-197B13 (1) (order this), CH73-387F7 (1) (order this)
    wwtr1Encodes: [cDNA] MGC:193975 (1) (order this), MGC:193988 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001037696 (1) 1401bp
    Genomic GenBank:CU468731 (1) 93652bp
    Select Tool
    Polypeptide UniProtKB:Q307I6 (1) 391aa
    Sequence Clusters UniGene:120269 (1)
    Sequence Information (all 19)
    OTHER wwtr1 GENE PAGES
  • Alliance (1)
  • Gene:568008 (1)
  • VEGA:OTTDARG00000032940 (1)
  • Ensembl(GRCz11):ENSDARG00000067719 (2)
  • ORTHOLOGY for wwtr1 (Chr: 22)
    CITATIONS (32)