Gene

wwtr1

ID
ZDB-GENE-051101-1
Name
WW domain containing transcription regulator 1
Symbol
wwtr1 Nomenclature History
Previous Names
  • taz (1)
Type
protein_coding_gene
Location
Chr: 22 Mapping Details/Browsers
Description
Predicted to enable transcription coactivator activity and transcription corepressor activity. Involved in regulation of gene expression. Acts upstream of with a positive effect on BMP signaling pathway. Acts upstream of or within several processes, including animal organ development; epithelial cell differentiation; and negative regulation of retinoic acid receptor signaling pathway. Predicted to be active in cytoplasm and nucleus. Is expressed in several structures, including brain; digestive system; endocrine system; head; and mesoderm. Orthologous to human WWTR1 (WW domain containing transcription regulator 1).
Genome Resources
Note
None
Comparative Information
Expression
All Expression Data
18 figures from 11 publications
Cross-Species Comparison
High Throughput Data
Thisse Expression Data
No data available
Wild Type Expression Summary
Phenotype
All Phenotype Data
24 figures from 10 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With wwtr1 Human Ortholog
No data available
Associated With wwtr1 Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR001202 WW domain
Homologous_superfamily IPR036020 WW domain superfamily
Domain Details Per Protein
Protein Length WW domain WW domain superfamily
UniProtKB:Q307I6 391
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-wwtr1 monoclonal IgG Rabbit
  • IHC
  • WB
Cell Signaling Technology, Inc.
14
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Comparative Orthology
Alliance
Gene Tree
Ensembl
Citations