ZFIN ID: ZDB-GENE-051014-1
Gene Name: sphingomyelin phosphodiesterase 2a, neutral membrane (neutral sphingomyelinase)
Gene Symbol: smpd2a
Sequence Ontology ID : SO:0000704

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Previous Names: smpd2, neutral SMase I (1), neutral sphingomyelinase (1), nSMase1 (1)

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(Including Attributions)
Location: Chr: 23 Mapping Details/Browsers
Nomenclature History
AUTOMATED DESCRIPTION
Exhibits sphingomyelin phosphodiesterase activity; involved in several processes, including MAPK cascade, cellular response to temperature stimulus, and membrane lipid metabolic process; localizes to  ...
GENE EXPRESSION
Directly Submitted Expression Data: 6 figures (8 images) from Thisse et al., 2004 [IMAGE:7156202]
Wild-type Stages, Structures: Gastrula:50%-epiboly (5.25h-5.66h) to Pharyngula:Prim-5 (24.0h-30.0h)
 
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Targeting reagents:
PHENOTYPE No data available
DISEASE ASSOCIATED WITH smpd2a HUMAN ORTHOLOG No data available
DISEASE ASSOCIATED WITH smpd2a VIA EXPERIMENTAL MODELS No data available
GENE ONTOLOGY
Ontology GO Term
Biological Process cellular response to temperature stimulus (more)
Cellular Component Golgi apparatus (more)
Molecular Function sphingomyelin phosphodiesterase activity (more)
GO Terms (all 10)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR005135 (1)
  • InterPro:IPR036691 (1)
  • Pfam:PF03372 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA smpd2a-001 (1) 1702
    GENE PRODUCT DESCRIPTION No description available
    INTERACTIONS AND PATHWAYS
    ANTIBODIES
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM smpd2a No data available
    MARKER RELATIONSHIPS
    smpd2aContained in: [Fosmid] CH1073-182O11 (1) (order this)
    smpd2aEncodes: [EST] IMAGE:7156202 (1) (order this)
    [cDNA] MGC:194512 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001030219 (1) 1263bp
    Genomic GenBank:CU570774 (1) 33235bp
    Select Tool
    Polypeptide UniProtKB:F1QUD7 (1) 421aa
    Sequence Clusters UniGene:47411 (1)
    Sequence Information (all 18)
    OTHER smpd2a GENE PAGES
  • Alliance (1)
  • Gene:567548 (1)
  • VEGA:OTTDARG00000034077 (1)
  • Ensembl(GRCz11):ENSDARG00000040523 (2)
  • ORTHOLOGY for smpd2a (Chr: 23)
    CITATIONS (16)