Gene

smpd2a

ID
ZDB-GENE-051014-1
Name
sphingomyelin phosphodiesterase 2a
Symbol
smpd2a Nomenclature History
Previous Names
  • smpd2
  • neutral SMase I (1)
  • neutral sphingomyelinase (1)
  • nSMase1 (1)
Type
protein_coding_gene
Location
Chr: 23 Mapping Details/Browsers
Description
Exhibits sphingomyelin phosphodiesterase activity. Involved in several processes, including cellular response to temperature stimulus; sphingolipid mediated signaling pathway; and sphingolipid metabolic process. Localizes to Golgi apparatus. Is expressed in yolk syncytial layer. Orthologous to human SMPD2 (sphingomyelin phosphodiesterase 2).
Genome Resources
Note
None
Expression
All Expression Data
No data available
Cross-Species Comparison
High Throughput Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
No data available
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With smpd2a Human Ortholog
No data available
Associated With smpd2a Via Experimental Models
No data available
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
Type InterPro ID Name
Domain IPR005135 Endonuclease/exonuclease/phosphatase
Family IPR038772 Sphingomyelin phosphodiesterase 2-like
Homologous_superfamily IPR036691 Endonuclease/exonuclease/phosphatase superfamily
Domain Details Per Protein
Protein Length Endonuclease/exonuclease/phosphatase Endonuclease/exonuclease/phosphatase superfamily Sphingomyelin phosphodiesterase 2-like
UniProtKB:B3DIS9 420
UniProtKB:F1QUD7 421
UniProtKB:Q4LEU0 420
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-smpd2a polyclonal Rabbit
1
Ab2-smpd2a polyclonal Rabbit
1
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations