Gene

esco2

ID
ZDB-GENE-050913-156
Name
establishment of sister chromatid cohesion N-acetyltransferase 2
Symbol
esco2 Nomenclature History
Previous Names
  • loc157570
  • si:dkey-217m5.6
  • un-named hi2865
  • unm hi2865
  • zgc:111795 (1)
Type
protein_coding_gene
Location
Chr: 20 Mapping Details/Browsers
Description
Predicted to have acetyltransferase activity. Involved in several processes, including positive regulation of cysteine-type endopeptidase activity involved in apoptotic process; sister chromatid cohesion; and tissue regeneration. Predicted to localize to chromatin. Is expressed in digestive system; heart; nervous system; otic vesicle; and pectoral fin. Used to study Roberts syndrome. Human ortholog(s) of this gene implicated in Roberts syndrome and SC phocomelia syndrome. Orthologous to human ESCO2 (establishment of sister chromatid cohesion N-acetyltransferase 2).
Genome Resources
Note
None
Expression
All Expression Data
6 figures from 3 publications
Cross-Species Comparison
High Throughput Data
Wild Type Expression Summary
Phenotype
All Phenotype Data
18 figures from 8 publications
Cross-Species Comparison
Alliance
Phenotype Summary
Mutations
Mutants
Sequence Targeting Reagents
Human Disease
Associated With esco2 Human Ortholog
Disease Ontology Term Multi-Species Data OMIM Term OMIM Phenotype ID
Roberts syndrome Alliance Roberts syndrome 268300
Roberts syndrome Alliance SC phocomelia syndrome 269000
Associated With esco2 Via Experimental Models
Gene Ontology
Protein Domains
Domain, Family, and Site Summary
No data available
Domain Details Per Protein
Protein Length
UniProtKB:Q5SPR8 609
Transcripts
Genome Browsers
Interactions and Pathways
No data available
Antibodies
Name Type Antigen Genes Isotype Host Organism Assay Source Citations
Ab1-esco2 polyclonal Rabbit
  • WB
2
Plasmids
No data available
Constructs
Marker Relationships
Sequences
Orthology
Ensembl Gene Tree
Citations