ZFIN ID: ZDB-GENE-050912-2
Gene Name: premelanosome protein b
Gene Symbol: pmelb
Sequence Ontology ID : SO:0000704

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Previous Name: silvb

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Location: Chr: 23 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 7 figures from 2 publications
Directly Submitted Expression Data: 6 figures (6 images) from Thisse et al., 2004 [IMAGE:7152383]
Wild-type Stages, Structures: Segmentation:20-25 somites (19.0h-22.0h) to Hatching:Long-pec (48.0h-60.0h)
  optic vesicle, retina, retinal pigmented epithelium
Curated Microarray Expression: GEO (1)
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
sa799 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • sa6748 Point Mutation Unknown Splice Site ENU
    sa17924 Point Mutation Unknown Splice Site ENU
  • Zebrafish International Resource Center (ZIRC) (order this)
  • European Zebrafish Resource Center (EZRC) (order this)
  • Targeting reagents: MO1-pmelb (1)
    PHENOTYPE
    Data: 2 figures from Burgoyne et al., 2015
    Observed in: melanosome assembly, melanosome localization, retinal pigmented epithelium melanosome
    DISEASE ASSOCIATED WITH pmelb HUMAN ORTHOLOGNo data available
    GENE ONTOLOGY
    Ontology GO Term
    Biological Process melanosome organization (more)
    Cellular Component integral component of membrane (more)
    GO Terms (all 6)
    PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000601 (1)
  • InterPro:IPR013783 (1)
  • InterPro:IPR022409 (1)
  • PROSITE:PS50093 (1)
  • Pfam:PF00801 (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA pmelb-001 (1) 2196
    pmelb-002 (1) 811
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM pmelb No data available
    MARKER RELATIONSHIPS
    pmelbContained in: [BAC] DKEY-18F23 (1) (order this)
    pmelbEncodes: [EST] IMAGE:7152383 (1) (order this)
    [cDNA] MGC:136221 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001033918 (1) 2219bp
    Genomic GenBank:BX465853 (1) 220945bp Blast at MegaBLAST
    Polypeptide UniProtKB:B8A520 (1) 616aa
    Sequence Clusters UniGene:75597 (1)
    Sequence Information (all 20)
    OTHER pmelb GENE PAGES
  • Alliance (1)
  • Gene:562810 (1)
  • VEGA:OTTDARG00000021269 (1)
  • Ensembl(GRCz10):ENSDARG00000033760 (1)
  • ORTHOLOGY for pmelb (Chr: 23)
    CITATIONS (23)