ZFIN ID: ZDB-GENE-050823-1
Gene Name: G protein-coupled receptor kinase 1 a
Gene Symbol: grk1a
Sequence Ontology ID : SO:0000704

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(Including Attributions)
Location: Chr: 1 Mapping Details/Browsers
Nomenclature History
GENE EXPRESSION
All Expression Data: 4 figures from 4 publications
Wild-type Stages, Structures: Larval:Day 4 (96.0h-120.0h) to Adult (90d-730d, breeding adult)
  epiphysis, eye, retinal photoreceptor layer, retinal rod cell (all 5) expand
MUTATIONS AND SEQUENCE TARGETING REAGENTS
Allele Type Localization Consequence Mutagen Suppliers
zko12a Small Deletion Unknown Unknown CRISPR
Targeting reagents: CRISPR1-grk1a (1), MO1-grk1a (1)
PHENOTYPE No data available
DISEASE ASSOCIATED WITH grk1a HUMAN ORTHOLOG
Disease Ontology Term OMIM Term OMIM Phenotype ID
Oguchi disease-2 Oguchi disease-2 613411
GENE ONTOLOGY
Ontology GO Term
Biological Process phosphorylation (more)
Molecular Function rhodopsin kinase activity (more)
GO Terms (all 13)
PROTEIN FAMILIES, DOMAINS AND SITES
  • InterPro:IPR000239 (1)
  • InterPro:IPR000719 (1)
  • InterPro:IPR000961 (1)
  • InterPro:IPR008271 (1)
  • InterPro:IPR011009 (1)
  • InterPro:IPR016137 (1)
  • InterPro:IPR017441 (1)
  • InterPro:IPR032965 (1)
  • InterPro:IPR036305 (1)
  • InterPro:IPR037716 (1)
  • PROSITE:PS00107 (1)
  • PROSITE:PS00108 (1)
  • PROSITE:PS50011 (1)
  • PROSITE:PS50132 (1)
  • PROSITE:PS51285 (1)
  • Pfam:PF00069 (1)
  • Pfam:PF00615 (1)
  • EC:2.7.11.- (1)
  • TRANSCRIPTS
    Type Name Length (bp) Analysis
    mRNA grk1a-001 (1) 4056
    GENE PRODUCT DESCRIPTION
    INTERACTIONS AND PATHWAYS
    ANTIBODIESNo data available
    PLASMIDSNo data available
    CONSTRUCTS WITH SEQUENCES FROM grk1a
    Tg(rho:grk1a)
    MARKER RELATIONSHIPS
    grk1aContained in: [BAC] CH211-129C2 (1) (order this)
    grk1aEncodes: [cDNA] MGC:195179 (1) (order this), MGC:195181 (1) (order this)
    SEQUENCE INFORMATION
    Type Accession # Length (bp/aa) Analysis
    RNA RefSeq:NM_001034181 (1) 2090bp
    Genomic GenBank:CU179747 (1) 162432bp
    Select Tool
    Polypeptide UniProtKB:Q1XHM0 (1) 563aa
    Sequence Clusters UniGene:87426 (1)
    Sequence Information (all 16)
    OTHER grk1a GENE PAGES
  • Alliance (1)
  • Gene:564152 (1)
  • VEGA:OTTDARG00000027019 (1)
  • Ensembl(GRCz10):ENSDARG00000058803 (1)
  • ORTHOLOGY for grk1a (Chr: 1)
    CITATIONS (23)