Gene
grk1b
- ID
- ZDB-GENE-050417-211
- Name
- G protein-coupled receptor kinase 1 b
- Symbol
- grk1b Nomenclature History
- Previous Names
-
- zgc:112194
- Type
- protein_coding_gene
- Location
- Chr: 5 Mapping Details/Browsers
- Description
- Exhibits rhodopsin kinase activity. Involved in cone photoresponse recovery. Is expressed in epiphysis; eye; retinal cone cell; and retinal photoreceptor layer.
- Genome Resources
- Note
- None
- All Expression Data
- 7 figures from 7 publications
- Cross-Species Comparison
- High Throughput Data
- No data available
- Thisse Expression Data
-
Wild Type Expression Summary
- All Phenotype Data
- 3 figures from Chrispell et al., 2018
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
Domain, Family, and Site Summary
| Type | InterPro ID | Name |
|---|---|---|
| Active_site | IPR008271 | Serine/threonine-protein kinase, active site |
| Domain | IPR000719 | Protein kinase domain |
| Domain | IPR000961 | AGC-kinase, C-terminal |
| Domain | IPR016137 | RGS domain |
| Family | IPR000239 | GPCR kinase |
| Homologous_superfamily | IPR011009 | Protein kinase-like domain superfamily |
| Homologous_superfamily | IPR036305 | RGS domain superfamily |
Domain Details Per Protein
| Protein | Length | AGC-kinase, C-terminal | GPCR kinase | Protein kinase domain | Protein kinase-like domain superfamily | RGS domain | RGS domain superfamily | Serine/threonine-protein kinase, active site |
|---|---|---|---|---|---|---|---|---|
|
UniProtKB:Q49HN0
|
559 | |||||||
|
UniProtKB:Q567A3
|
559 |
Interactions and Pathways
No data available
| Name | Type | Antigen Genes | Isotype | Host Organism | Assay | Source | Citations |
|---|---|---|---|---|---|---|---|
| Ab3-grk1 | monoclonal | IgG1 | Mouse |
|
Affinity BioReagents (Thermo Fisher Scientific)
|
2 |
Plasmids
No data available
- Gene Tree
- Ensembl